Results 51 to 60 of about 100,610 (290)
Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei [PDF]
, 2017 The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite.
Agop-Nersesian, Carolina +5 more
core +2 more sources
LC3-associated phagocytosis at a glance
Journal of Cell Science, 2019 ABSTRACT Classically, canonical autophagy has been considered a survival mechanism initiated in response to nutrient insufficiency. We now understand that autophagy functions in multiple scenarios where it is necessary to maintain homeostasis.
Bradlee L. Heckmann, Douglas R. Green
openaire +3 more sources
Evaluation of the expression of LC3-II and BECLIN1 genes of autophagy pathway in patients with hematological malignancies [PDF]
Caspian Journal of Internal Medicine, 2023 Background: Autophagy is a pathway for the degradation of cytoplasmic components, which plays an essential role in various cellular and physiological processes, including cell renewal and survival, and immune responses.
Hossein Ayatollahi +6 more
doaj
Capsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent manner [PDF]
, 2016 Bladder cancer (BC) is a common urologic tumor characterized by high risk of recurrence and mortality. Capsaicin (CPS), used as an intravesical drug for overactive bladder, was demonstrated to induce cell death in different cancer cells including BC ...
Amantini, C +6 more
core +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Frontiers in Physiology, 2021 The cardioprotection of exercise preconditioning (EP) has been well documented. EP can be divided into two phases that are the induction of exercise preconditioning (IEP) and the protection of exercise preconditioning (PEP).
Dong-Feng Wan +3 more
doaj +1 more source
Cannabidiol stimulates AML-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner [PDF]
, 2015 Glioma stem-like cells (GSCs) correspond to a tumor cell subpopulation, involved in glioblastoma multiforme (GBM) tumor ini- tiation and acquired chemoresistance.
Amantini, Consuelo +7 more
core +2 more sources
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Crystal structure of 25,27-dibenzyloxy-26-benzoyloxy-28-hydroxycalix[ 4]arene, C49H40O5
Zeitschrift für Kristallographie - New Crystal Structures, 2006 C49H40O5, triclinic, P1̅ (no. 2), a = 10.8865(2) Å, b = 18.2743(3) Å, c = 18.3545(3) Å, α = 85.166(1)°, β = 86.233(1)°, γ = 84.268(1)°, V = 3614.3 Å3, Z = 4, Rgt(F) = 0.054, wRref(F2) = 0.148, T = 120 K.
Kuhn P., Matt D., Toupet L., Louati A.
doaj +1 more source
The Journal of Poultry Science, 2018 Autophagy, an intracellular bulk protein degradation system in skeletal muscle, is increased under catabolic conditions resulting in muscle atrophy. This study aimed to investigate the effects of insulin, insulin-like growth factor (IGF)-I, and amino ...
Kazuki Nakashima, Aiko Ishida
doaj +1 more source