Results 41 to 50 of about 42,983 (262)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Innovative Behavior in the Workplace: An Empirical Study of Moderated Mediation Model of Self-Efficacy, Perceived Organizational Support, and Leader–Member Exchange

open access: yesBehavioral Sciences, 2021
Recently, most organizations, from for-profit organizations to nonprofit organizations, are facing a rapidly changing environment and increased uncertainty.
Woo-Sung Choi   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Leader–member exchange (LMX), job autonomy, and creative work involvement

open access: yes, 2012
Researchers have claimed that high quality of supervisor–employee relationships (i.e., leader– member exchange; LMX) fosters creativity at work. Moreover, researchers have acknowledged that this relationship is not clear-cut but rather complex.
Daniel Spurk   +5 more
core   +1 more source

Economic and social leader-member exchange relationships [PDF]

open access: yes, 2012
This exploratory study investigated the link between economic and social leader-member exchange relationships and follower work performance and organizational citizenship behavior.
Kuvaas, Bård   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Leader member exchange dan keterikatan kerja pegawai honorer

open access: yes, 2022
This study aims to determine the relationship between Leader Member Exchange (LMX) and work engagement on honorary employees. This research is a correlational quantitative research. The subjects in this study were 148 temporary employees.
Prasetyo, Yanto   +3 more
core   +1 more source

Spanning leader–subordinate relationships through negative interactions : An examination of leader–member exchange breaches [PDF]

open access: yes, 2020
The study aims to discover the dynamic and processual nature of a supervisory relationship (here a leader–member exchange) through a novel, theoretical concept termed leader–member exchange breach, and by examining the characteristics of negative ...
Kangas, Hilpi
core   +1 more source

Analisis Kesejahteraan Psikologis Karyawan dan Kualitas Interaksi Bawahan Berdasarkan Kepribadian Atasan

open access: yesHumanitas: Indonesian Psychological Journal, 2018
This research background was the low indicator of employee well-being (EWB) in Jakarta that derived from several employee surveys. One factor that has significant influence to EWB is management leadership.
Nuri Sadida, Nurindah Fitria
doaj   +1 more source

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