Results 21 to 30 of about 2,058,783 (273)
A growing number of studies in humans demonstrate the involvement of vestibular information in tasks that are seemingly remote from well-known functions such as space constancy or postural control.
Fred W Mast +6 more
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Phosphoproteomics identifies microglial Siglec‐F inflammatory response during neurodegeneration
Alzheimer’s disease (AD) is characterized by the appearance of amyloid‐β plaques, neurofibrillary tangles, and inflammation in brain regions involved in memory. Using mass spectrometry, we have quantified the phosphoproteome of the CK‐p25, 5XFAD, and Tau
Nader Morshed +12 more
doaj +1 more source
Neural effects of propofol-induced unconsciousness and its reversal using thalamic stimulation
The specific circuit mechanisms through which anesthetics induce unconsciousness have not been completely characterized. We recorded neural activity from the frontal, parietal, and temporal cortices and thalamus while maintaining unconsciousness in non ...
André M Bastos +10 more
doaj +1 more source
Structural plasticity of dendritic secretory compartments during LTP-induced synaptogenesis
Long-term potentiation (LTP), an increase in synaptic efficacy following high-frequency stimulation, is widely considered a mechanism of learning. LTP involves local remodeling of dendritic spines and synapses.
Yelena D Kulik +4 more
doaj +1 more source
Two-photon microscopy is a powerful tool for studying neuronal activity but cannot easily image deeper cortical layers. Here, the authors design a custom microscope for three-photon microscopy and use it to reveal response properties of layer 5, 6, and ...
Murat Yildirim +3 more
doaj +1 more source
Emergence of spatiotemporal invariance in large neuronal ensembles in rat barrel cortex.
Invariant sensory coding is the robust coding of some sensory information (e.g. stimulus type) despite major changes in other sensory parameters (e.g. stimulus strength).
Nathan S Jacobs +6 more
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Introduction We tested whether Alzheimer's disease (AD) pathology predicts memory deficits in non‐demented older adults through its effects on medial temporal lobe (MTL) subregional volume. Methods Thirty‐two, non‐demented older adults with cerebrospinal
Jenna N. Adams +12 more
doaj +1 more source
Alcohol is thought to lead to neuroadaptive changes, although the underlying molecular mechanisms are unclear. Here, the authors find ethanol treatment alters GABAB-receptor expression via fragile-X mental retardation protein in mice, leading to ...
Sarah A. Wolfe +10 more
doaj +1 more source
Despite extensive research into both synaptic and morphological changes, surprisingly little is known about dendritic function in fragile X syndrome (FXS).
Darrin H. Brager +2 more
doaj +1 more source
Protective Effects of Crocus Sativus L. Extract and Crocin against Chronic-Stress Induced Oxidative Damage of Brain, Liver and Kidneys in Rats [PDF]
Purpose: Chronic stress has been reported to induce oxidative damage of the brain. A few studies have shown that Crocus Sativus L., commonly known as saffron and its active constituent crocin may have a protective effect against oxidative stress.
Ahmad Reza Bandegi +3 more
doaj +1 more source

