Results 91 to 100 of about 3,742,705 (301)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

COMPARATIVE STUDY OF BIOLOGICALLY ACTIVE COMPOUNDS COMPOSITION IN THE LEAVES AND FRUITS OF HEDERA CAUCASICA

open access: yesРазработка и регистрация лекарственных средств, 2019
A comparative study of the biologically active compounds (BAC) composition of alcoholic extracts of leaves and fruits was carried out by GLC-MS. It is shown that the BAC composition of leaves of Hedera caucasica is more extensive: the structure of 22 ...
V. M. Baeva   +2 more
doaj  

Evaluation of morphological and production characteristics and nutritive value of 47 lucerne cultivars/lines in temperate Australia

open access: yesPlant Production Science, 2019
Forty-seven lucerne varieties/lines were examined to quantify their morphological, production characteristics, and nutritive values in southeastern Australia.
Lili Nan   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Sprawl Leaves its Footprint in Water [PDF]

open access: yes, 2001
The Environmental and Energy Study Institute held a Congressional briefing on water pollution resulting from increased motor vehicle traffic associated with urban sprawl. The briefing featured information from recent studies by the National Water Quality
Ron Grandon
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Antimicrobial activity screening of isolated flavonoids from Azadirachta indica leaves [PDF]

open access: yesJournal of the Serbian Chemical Society, 2011
The antimicrobial activities of two flavonoids, namely genistein 7-O-glucoside (1) and (–)-epi-catechin (2), isolated from Azadirachta indica A. Juss (neem) leaves, were evaluated against five fungal species, viz: Alternaria alternata (Fr.) Keissler ...
QUDSIA KANWAL   +3 more
doaj  

HPLC-DAD-ESI-MS Analysis of Flavonoids from Leaves of Different Cultivars of Sweet Osmanthus

open access: yesMolecules, 2016
Osmanthus fragrans Lour. has traditionally been a popular ornamental plant in China. In this study, ethanol extracts of the leaves of four cultivar groups of O.
Yiguang Wang   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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