Results 11 to 20 of about 104,017 (255)
The Lectin Pathway of Complement and Rheumatic Heart Disease [PDF]
Frontiers in Pediatrics, 2015 The innate immune system is the first line of host defense against infection and is comprised of humoral and cellular mechanisms that recognize potential pathogens within minutes or hours of entry.
Marcia Holsbach Beltrame +4 more
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Lectin complement pathway and diabetes mellitus in the pathogenesis of membranous nephropathy [PDF]
Folia Medica, 2023 Introduction: Membranous nephropathy (MN) is a glomerulonephritis with growing incidence and its pathogenesis still remains unclear, despite discoveries of many new antigens.
Irina Y. Zdravkova +2 more
doaj +3 more sources
Dengue and the Lectin Pathway of the Complement System. [PDF]
Viruses, 2021 Dengue is a mosquito-borne viral disease causing significant health and economic burdens globally. The dengue virus (DENV) comprises four serotypes (DENV1-4). Usually, the primary infection is asymptomatic or causes mild dengue fever (DF), while secondary infections with a different serotype increase the risk of severe dengue disease (dengue ...
Kraivong R +4 more
europepmc +6 more sources
Инфекция и иммунитет, 2022 The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova +1 more
doaj +1 more source
Lectin complement pathway proteins in healthy individuals [PDF]
Clinical and Experimental Immunology, 2017 Summary Since the discovery of the lectin pathway of complement activation, numerous clinical cohorts have been examined for one or more proteins, with the intention of uncovering the functions of the proteins or with the aim of discovering new biomarkers or diagnostic tools. To unveil the abnormal, it is pivotal to know the normal.
Troldborg, Anne +5 more
openaire +4 more sources
Mitochondria and the Lectin Pathway of Complement [PDF]
Journal of Biological Chemistry, 2013 Mitochondria, the powerhouses of our cells, are remnants of a eubacterial endosymbiont. Notwithstanding the evolutionary time that has passed since the initial endosymbiotic event, mitochondria have retained many hallmarks of their eubacterial origin. Recent studies have indicated that during perturbations of normal homeostasis, such as following acute
Brinkmann, Christel R +8 more
openaire +4 more sources
The complement lectin pathway after cardiac arrest [PDF]
Scandinavian Journal of Immunology, 2018 AbstractThe lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate the levels of the LP proteins in out‐of‐hospital cardiac arrest patients, and to compare these with healthy individuals.
S. F. Haugaard +5 more
openaire +3 more sources
Use of C4d as a diagnostic tool to classify membranoproliferative glomerulonephritis
Nefrología, 2017 Background: Membranoproliferative glomerulonephritis (MPGN type I, II and III) was reclassified in 2013 as MPGN and C3 glomerulopathy (C3G) based on the complement system activation mechanism.
Nirupama Gupta +3 more
doaj +3 more sources
Lectins and traffic in the secretory pathway [PDF]
FEBS Letters, 2000 Evidence is accumulating that intracellular animal lectins play important roles in quality control and glycoprotein sorting along the secretory pathway. Calnexin and calreticulin in conjunction with associated chaperones promote correct folding and oligomerization of many glycoproteins in the endoplasmic reticulum (ER).
Hauri, H. +3 more
openaire +3 more sources
Acta Pharmaceutica Sinica B, 2015 Traditionally, determination of inhibitory potency of complement inhibitors is performed by the hemolytic assay. However, this assay is not applicable to the lectin pathway, thus impeding the understanding of complement inhibitors against the overall ...
Mulu Wu +3 more
doaj +1 more source