Results 11 to 20 of about 103,608 (291)

Proteins of the lectin pathway of the complement system activation: immunobiological functions, genetics and involvement in the pathogenesis of human diseases

Инфекция и иммунитет, 2022
The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova, Sergey Yu. Tereshchenko   +1 more
doaj   +3 more sources

The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury—Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor [PDF]

Frontiers in Immunology, 2018
Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality in modern medicine. Early reperfusion accomplished by primary percutaneous coronary intervention is pivotal for reducing myocardial damage in ST elevation AMI.
Anneza Panagiotou, Marten Trendelenburg, Marten Trendelenburg, Michael Osthoff, Michael Osthoff   +4 more
doaj   +2 more sources

Revisiting the interaction between complement lectin pathway protease MASP-2 and SARS-CoV-2 nucleoprotein [PDF]

Frontiers in Immunology
Complement activation is considered to contribute to the pathogenesis of severe SARS-CoV-2 infection, mainly by generating potent immune effector mechanisms including a strong inflammatory response.
Isabelle Bally, Guillaume Drumont, Véronique Rossi, Serafima Guseva, Maiia Botova, Jean-Baptiste Reiser, Michel Thépaut, Sebastian Dergan Dylon, Chantal Dumestre-Pérard, Chantal Dumestre-Pérard, Christine Gaboriaud, Franck Fieschi, Martin Blackledge, Pascal Poignard, Pascal Poignard, Nicole M. Thielens   +15 more
doaj   +2 more sources

Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy [PDF]

Experimental Hematology & Oncology, 2021
Hematopoietic stem cell transplantation-associated thrombotic microangiopathy (HSCT-TMA) is a life-threatening syndrome that occurs in adult and pediatric patients after hematopoietic stem cell transplantation.
Eleni Gavriilaki, Vincent T. Ho, Wilhelm Schwaeble, Thomas Dudler, Mohamed Daha, Teizo Fujita, Sonata Jodele   +6 more
doaj   +2 more sources

The Lectin Pathway of Complement and Rheumatic Heart Disease [PDF]

Frontiers in Pediatrics, 2015
The innate immune system is the first line of host defense against infection and is comprised of humoral and cellular mechanisms that recognize potential pathogens within minutes or hours of entry.
Marcia Holsbach Beltrame, Sandra Jeremias Catarino, Isabela eGoeldner, Angelica Beate Winter Boldt, Iara eDe Messias Reason   +4 more
doaj   +3 more sources

MAp34 Regulates the Non-specific Cell Immunity of Monocytes/Macrophages and Inhibits the Lectin Pathway of Complement Activation in a Teleost Fish [PDF]

Frontiers in Immunology, 2020
The lectin pathway of the complement system is one of the main components of innate immunity, which plays a pivotal role in the defense against infectious microorganisms and maintains immune homeostasis.
Liangliang Mu, Xiaoxue Yin, Hairong Wu, Kailiang Han, Zheng Guo, Jianmin Ye   +5 more
doaj   +2 more sources

Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels. [PDF]

PLoS Neglected Tropical Diseases, 2020
BackgroundDeposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement.
Hellen Weinschutz Mendes, Angelica Beate Winter Boldt, Ewalda von Rosen Seeling Stahlke, Jens Christian Jensenius, Steffen Thiel, Iara J Taborda Messias-Reason   +5 more
doaj   +2 more sources

Lectin pathway components and autoantibodies as novel immunological biomarkers in systemic lupus erythematosus (SLE) patients from Western India. [PDF]

Sci Rep
Rai K, Khatri R, Jose A, Konkar H, Nadkar M, Rajadhyaksha A, Roumenina L, Parande A, Bitla G, Padwal V, Madkaikar M, Pradhan V.   +11 more
europepmc   +3 more sources

Distinction of early complement classical and lectin pathway activation via quantification of C1s/C1-INH and MASP-1/C1-INH complexes using novel ELISAs. [PDF]

Front Immunol, 2022
Hurler L, Toonen EJM, Kajdácsi E, van Bree B, Brandwijk RJMGE, de Bruin W, Lyons PA, Bergamaschi L, Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration, Sinkovits G, Cervenak L, Würzner R, Prohászka Z.   +12 more
europepmc   +3 more sources

The Lectin Pathway of the Complement System-Activation, Regulation, Disease Connections and Interplay with Other (Proteolytic) Systems. [PDF]

Int J Mol Sci
Dobó J, Kocsis A, Farkas B, Demeter F, Cervenak L, Gál P.   +5 more
europepmc   +3 more sources