Results 21 to 30 of about 103,608 (291)

Guianensin, a Blackfly Salivary Protein, Inhibits the Lectin Pathway of Complement. [PDF]

J Med Chem
Valenzuela Leon PC, Ring ME, Nishiduka E, Bonilla B, Cruz P, Martinez EP, Percopo C, Calvo E.   +7 more
europepmc   +2 more sources

Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab. [PDF]

Immunobiology, 2020
Rambaldi A, Gritti G, Micò MC, Frigeni M, Borleri G, Salvi A, Landi F, Pavoni C, Sonzogni A, Gianatti A, Binda F, Fagiuoli S, Di Marco F, Lorini L, Remuzzi G, Whitaker S, Demopulos G.   +16 more
europepmc   +3 more sources

Lectin complement pathway and diabetes mellitus in the pathogenesis of membranous nephropathy [PDF]

Folia Medica, 2023
Introduction: Membranous nephropathy (MN) is a glomerulonephritis with growing incidence and its pathogenesis still remains unclear, despite discoveries of many new antigens.
Irina Y. Zdravkova, Eduard E. Tilkiyan, Desislava M. Bozhkova   +2 more
doaj   +3 more sources

Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors. [PDF]

Front Immunol, 2020
Boldt ABW, Oliveira-Toré CF, Kretzschmar GC, Weinschutz Mendes H, Stinghen ST, Andrade FA, Bumiller-Bini V, Gonçalves LB, Braga ACM, Stahlke EVRS, Velavan TP, Thiel S, de Messias-Reason IJT.   +12 more
europepmc   +3 more sources

Lectin complement pathway proteins in healthy individuals [PDF]

Clinical and Experimental Immunology, 2017
Summary Since the discovery of the lectin pathway of complement activation, numerous clinical cohorts have been examined for one or more proteins, with the intention of uncovering the functions of the proteins or with the aim of discovering new biomarkers or diagnostic tools. To unveil the abnormal, it is pivotal to know the normal.
Troldborg, Anne, Hansen, Annette Gudmann, Hansen, Søren W K, Jensenius, Jens Christian, Stengaard-Pedersen, Kristian, Thiel, Steffen   +5 more
openaire   +4 more sources

The complement lectin pathway after cardiac arrest [PDF]

Scandinavian Journal of Immunology, 2018
AbstractThe lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate the levels of the LP proteins in out‐of‐hospital cardiac arrest patients, and to compare these with healthy individuals.
S. F. Haugaard, A. N. Jeppesen, A. Troldborg, H. Kirkegaard, S. Thiel, A.‐M. Hvas   +5 more
openaire   +3 more sources

Use of C4d as a diagnostic tool to classify membranoproliferative glomerulonephritis

Nefrología (English Edition), 2017
Background: Membranoproliferative glomerulonephritis (MPGN type I, II and III) was reclassified in 2013 as MPGN and C3 glomerulopathy (C3G) based on the complement system activation mechanism.
Nirupama Gupta, Dara N. Wakefield, William L. Clapp, Eduardo H. Garin   +3 more
doaj   +3 more sources

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.

PLoS Pathogens, 2012
The complement system plays a key role in host defense against pneumococcal infection. Three different pathways, the classical, alternative and lectin pathways, mediate complement activation.
Youssif M Ali, Nicholas J Lynch, Kashif S Haleem, Teizo Fujita, Yuichi Endo, Soren Hansen, Uffe Holmskov, Kazue Takahashi, Gregory L Stahl, Thomas Dudler, Umakhanth V Girija, Russell Wallis, Aras Kadioglu, Cordula M Stover, Peter W Andrew, Wilhelm J Schwaeble   +15 more
doaj   +1 more source

Lectins and traffic in the secretory pathway [PDF]

FEBS Letters, 2000
Evidence is accumulating that intracellular animal lectins play important roles in quality control and glycoprotein sorting along the secretory pathway. Calnexin and calreticulin in conjunction with associated chaperones promote correct folding and oligomerization of many glycoproteins in the endoplasmic reticulum (ER).
Hauri, H., Appenzeller, C., Kuhn, F., Nufer, O.   +3 more
openaire   +3 more sources

Development of a C3c-based ELISA method for the determination of anti-complementary potency of Bupleurum polysaccharides

Acta Pharmaceutica Sinica B, 2015
Traditionally, determination of inhibitory potency of complement inhibitors is performed by the hemolytic assay. However, this assay is not applicable to the lectin pathway, thus impeding the understanding of complement inhibitors against the overall ...
Mulu Wu, Hong Li, Yunyi Zhang, Daofeng Chen   +3 more
doaj   +1 more source