Results 41 to 50 of about 126,935 (188)

The Complement System of Agnathans

open access: yesFrontiers in Immunology, 2018
Agnathans (lamprey and hagfish) are a group of primitive jawless fish. Jawed vertebrates possess adaptive immunity including immunoglobulins, while agnathans lack immunoglobulins but have alternative adaptive immunity in which variable lymphocyte ...
Misao Matsushita
doaj   +1 more source

PDGFB as a vascular normalization agent in an ovarian cancer model treated with a gamma-secretase inhibitor [PDF]

open access: yes, 2019
Ovarian cancer is the fifth leading cause of cancer-related deaths in women. In the past 20 years, the canonical types of drugs used to treat ovarian cancer have not been replaced and the survival rates have not changed.
Abramovich, Dalhia Nurit   +7 more
core   +1 more source

Isolation and characterization of novel primary cells from the human distal outflow pathway

open access: yesScientific Reports, 2021
Ocular hypertension occurs due to increased resistance to aqueous humor removal through the conventional outflow pathway. Unlike the proximal region of the conventional outflow pathway, the distal region has not been well studied, mostly due to lack of ...
Uttio Roy Chowdhury   +4 more
doaj   +1 more source

Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. [PDF]

open access: yes, 2019
Fam20C is a secreted protein kinase mutated in Raine syndrome, a human skeletal disorder. In vertebrates, bone and enamel proteins are major Fam20C substrates.
Adina Gerson-Gurwitz   +70 more
core   +2 more sources

OsEUL lectin gene expression in rice : stress regulation, subcellular localization and tissue specificity [PDF]

open access: yes, 2020
The Euonymus lectin (EUL) family is a unique group of carbohydrate-binding proteins that is omnipresent in plants. Sequences encoding EUL-related lectins have been retrieved from all completely sequenced plant genomes.
De Zaeytijd, Jeroen   +9 more
core   +1 more source

MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement Activation and Phagocytosis

open access: yesJournal of Innate Immunity, 2021
Activation of the complement system is mediated by the interaction between pathogens and pattern recognition molecules (PRMs); mannose-binding lectin (MBL), ficolins, and collectin-10/-11 from the lectin pathway and C1q from the classical pathway. Lectin
Anne Rosbjerg   +3 more
doaj   +1 more source

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis. [PDF]

open access: yes, 2016
Cholesterol crystals (CC) play an essential role in the formation of atherosclerotic plaques. CC activate the classical and the alternative complement pathways, but the role of the lectin pathway is unknown.
Genster, Ninette   +4 more
core   +1 more source

Pattern recognition receptors in antifungal immunity [PDF]

open access: yes, 2014
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D   +2 more
core   +2 more sources

Research advances on plant lectin receptor-like kinases in abiotic stress response

open access: yesGuangxi Zhiwu, 2023
Plants are exposed to various stress during their growth and development, and abiotic stress is one of the most significant factors. Receptor-like kinases (RLKs) are widely present in plants that can quickly and effectively respond to stress, ultimately ...
Menglong WANG   +3 more
doaj   +1 more source

Glycobiology of the olfactory system [PDF]

open access: yes, 1998
The olfactory system is a highly plastic region of the nervous system. Continuous remodeling of neuronal circuits in the olfactory bulb takes place throughout life as a result of constant turnover of primary sensory olfactory neurons in the periphery ...
Plendl, J., Sinowatz, Fred
core   +1 more source

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