Results 41 to 50 of about 2,389,068 (178)

The complement lectin pathway after cardiac arrest [PDF]

open access: yesScandinavian Journal of Immunology, 2018
AbstractThe lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate the levels of the LP proteins in out‐of‐hospital cardiac arrest patients, and to compare these with healthy individuals.
S. F. Haugaard   +5 more
openaire   +3 more sources

The Complement System of Agnathans

open access: yesFrontiers in Immunology, 2018
Agnathans (lamprey and hagfish) are a group of primitive jawless fish. Jawed vertebrates possess adaptive immunity including immunoglobulins, while agnathans lack immunoglobulins but have alternative adaptive immunity in which variable lymphocyte ...
Misao Matsushita
doaj   +1 more source

Critical role of lectin pathway mediated by MBL-associated serine proteases in complement activation for the pathogenesis in systemic lupus erythematosus

open access: yesHeliyon, 2023
In complement activation system, although the classical pathway has shown to play a critical role for the pathogenesis of SLE, the role of lectin pathway has remained unknown in the pathogenesis of SLE.
Yuko Asanuma   +6 more
doaj  

Isolation and characterization of novel primary cells from the human distal outflow pathway

open access: yesScientific Reports, 2021
Ocular hypertension occurs due to increased resistance to aqueous humor removal through the conventional outflow pathway. Unlike the proximal region of the conventional outflow pathway, the distal region has not been well studied, mostly due to lack of ...
Uttio Roy Chowdhury   +4 more
doaj   +1 more source

MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement Activation and Phagocytosis

open access: yesJournal of Innate Immunity, 2021
Activation of the complement system is mediated by the interaction between pathogens and pattern recognition molecules (PRMs); mannose-binding lectin (MBL), ficolins, and collectin-10/-11 from the lectin pathway and C1q from the classical pathway. Lectin
Anne Rosbjerg   +3 more
doaj   +1 more source

Enhancement of lectin pathway haemolysis by immunoglobulins

open access: yesClinical and Experimental Immunology, 1999
SUMMARYWe recently reported that indicator sheep erythrocytes (E) coated with mannan and sensitized with mannan-binding lectin (MBL) (E-M-MBL) are lysed by human serum in the absence of calcium via the lectin pathway of complement activation by a process which requires alternative pathway amplification and is associated with increased binding of and ...
Henry Gewurz   +4 more
openaire   +3 more sources

The Lectin Pathway of the Complement System—Activation, Regulation, Disease Connections and Interplay with Other (Proteolytic) Systems

open access: yesInternational Journal of Molecular Sciences
The complement system is the other major proteolytic cascade in the blood of vertebrates besides the coagulation–fibrinolytic system. Among the three main activation routes of complement, the lectin pathway (LP) has been discovered the latest, and it is ...
J. Dobó   +5 more
semanticscholar   +1 more source

Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19

open access: yesFrontiers in Immunology, 2022
Complement plays an important role in the direct defense to pathogens, but can also activate immune cells and the release of pro-inflammatory cytokines. However, in critically ill patients with COVID-19 the immune system is inadequately activated leading
Janina Niederreiter   +7 more
semanticscholar   +1 more source

Research advances on plant lectin receptor-like kinases in abiotic stress response

open access: yesGuangxi Zhiwu, 2023
Plants are exposed to various stress during their growth and development, and abiotic stress is one of the most significant factors. Receptor-like kinases (RLKs) are widely present in plants that can quickly and effectively respond to stress, ultimately ...
Menglong WANG   +3 more
doaj   +1 more source

Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum.

open access: yesPLoS Pathogens, 2019
Ecotin is a serine protease inhibitor produced by hundreds of microbial species, including pathogens. Here we show, that ecotin orthologs from Escherichia coli, Yersinia pestis, Pseudomonas aeruginosa and Leishmania major are potent inhibitors of MASP-1 ...
Zoltán Attila Nagy   +10 more
doaj   +1 more source

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