Results 81 to 90 of about 16,640 (230)
Sequence analysis of the 3-untranslated region of HSP70 (type I) genes in the genus Leishmania: Its usefulness as a molecular marker for species identification [PDF]
, 2015 Background: The Leishmaniases are a group of clinically diverse diseases caused by parasites of the genus Leishmania. To distinguish between species is crucial for correct diagnosis and prognosis as well as for treatment decisions.
Cañavate, Carmen +5 more
core +1 more source
Biomedicine & Pharmacotherapy, 2018 Leishmania (Leishmania) amazonensis and Leishmania infantum (=Leishmania chagasi) are protozoa that cause American cutaneous and visceral leishmaniasis, respectively. These diseases show a high incidence in developing countries such as Brazil. The treatments used for leishmaniasis are still limited due to their high cost and toxicity.
Bruno José Martins, Da Silva +5 more
openaire +2 more sources
Efficacy of a diarylheptanoid derivative against Leishmania amazonensis [PDF]
Memórias do Instituto Oswaldo Cruz, 2003 The activity of several diarylheptanoid derivatives (curcuminoids) was previously evaluated against Leishmania amazonensis promastigotes and among them the most active compound was the [1-(4-methoxy-phenyl)-7-(3,4-methoxy-4-hydroxy-phenyl)-1,6-heptadien-3, 5-dione]. This derivative was chosen to be assayed in vivo in a treatment trial.
Luciana Vignólio Alves +3 more
openaire +4 more sources
Characterization of Sv129 Mice as a Susceptible Model to Leishmania amazonensis
Frontiers in Medicine, 2019 Leishmaniasis is a complex of neglected diseases caused by parasites of the genus Leishmania, such as Leishmania (Leishmania) amazonensis, the ethiologic agent of diffuse cutaneous leishmaniasis in Brazil. In this work, we investigated a new experimental
Júlio Souza dos-Santos +9 more
doaj +1 more source
Health Benefits and Therapeutic Potential of Quercetin
Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley +1 more source
Frontiers in Immunology, 2019 CBA mice macrophages (MØ) control infection by Leishmania major and are susceptive to Leishmania amazonensis, suggesting that both parasite species induce distinct responses that play important roles in infection outcome.
Juliana Perrone Bezerra de Menezes +22 more
doaj +1 more source
Piplartine as an Innovative Natural Product With Dual Antiparasitic and Immunomodulatory Actions
Journal of Immunology Research, Volume 2026, Issue 1, 2026.Neglected tropical diseases (NTDs) remain a major global health burden, disproportionately affecting low‐ and middle‐income regions and demanding innovative therapeutic strategies. This review summarizes current evidence on piplartine (piperlongumine), a naturally occurring amide from Piper species with broad antiparasitic and immunomodulatory ...
Lucas Fukui-Silva +4 more
wiley +1 more source
Semina: Ciências Agrárias, 2012 Leishmaniasis are antropozoonoses involving various species of Leishmania and hosts, with variable clinical presentations and considered of great importance to public health.
Patrícia Mendes Pereira +5 more
doaj
Cell-to-cell transfer of Leishmania amazonensis amastigotes is mediated by immunomodulatory LAMP-rich parasitophorous extrusions [PDF]
, 2014 The last step of Leishmania intracellular life cycle is the egress of amastigotes from the host cell and their uptake by adjacent cells. Using multidimensional live imaging of long-term-infected macrophage cultures we observed that Leishmania amazonensis
Goto, Hiro +6 more
core +3 more sources
The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
wiley +1 more source