Results 71 to 80 of about 59,340 (183)

Proteomic Analysis Reveals a Predominant NFE2L2 (NRF2) Signature in Canonical Pathway and Upstream Regulator Analysis of Leishmania-Infected Macrophages

Frontiers in Immunology, 2019
CBA mice macrophages (MØ) control infection by Leishmania major and are susceptive to Leishmania amazonensis, suggesting that both parasite species induce distinct responses that play important roles in infection outcome.
Juliana Perrone Bezerra de Menezes, Ricardo Khouri, Ricardo Khouri, Camila Victoria Sousa Oliveira, Antonio Luis de Oliveira Almeida Petersen, Tais Fontoura de Almeida, Tais Fontoura de Almeida, Flávia R. L. Mendes, Amanda do Amor Divino Rebouças, Amanda Lopes Lorentz, Nívea Farias Luz, Jonilson Berlink Lima, Pablo Ivan Pereira Ramos, Rodrigo Pedro Soares, Jeronimo Nunes Rugani, Gregory A. Buck, Marco Aurélio Krieger, Fabrício Klerynton Marchini, Áislan de Carvalho Vivarini, Ulisses Gazos Lopes, Valéria de Matos Borges, Patricia Sampaio Tavares Veras, Patricia Sampaio Tavares Veras   +22 more
doaj   +1 more source

Studies on immunology of Leishmania mexicana [PDF]

, 2007
Leishmaniasis is a worldwide disease prevalent in many tropical and sub tropical countries. Treatment of Leishmaniasis by chemotherapy is not wholly effective and is usually accompanied by unpleasant side effects.
Rezvan, H, Rezvan, Hossein
core  

Domestic feline cutaneous leishmaniasis in the municipality of Ribas do Rio Pardo, Mato Grosso do Sul state, Brazil: a case report

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
Cutaneous leishmaniases are anthropozoonoses that involve many species of Leishmania and a wide variety of wild mammalian hosts, thus presenting high importance to public health.
AI Souza, VLB Nunes, VM Borralho, EAY Ishikawa   +3 more
doaj   +1 more source

Modulation of fibroblast behavior by Leishmania: a pathway to understanding disease progression in cutaneous leishmaniasis

BMC Microbiology
Leishmaniasis is a parasitic infection caused by obligatory intracellular protozoa of the Leishmania genus. Macrophages are the main cell for Leishmania parasites that play a key role in immune response against it.
Tarcisio Navegante de Queiroz Filho, Brenda Furtado Costa, Ana Paula Drummond Rodrigues   +2 more
doaj   +1 more source

Extracellular Vesicles Released by Leishmania (Leishmania) amazonensis Promote Disease Progression and Induce the Production of Different Cytokines in Macrophages and B-1 Cells

Frontiers in Microbiology, 2018
The extracellular vesicles (EVs) released by Leishmania can contribute to the establishment of infection and host immunomodulation. In this study, we characterized the shedding of EVs from Leishmania (Leishmania) amazonensis promastigotes.
Fernanda Marins Costa Barbosa, Talita Vieira Dupin, Mayte dos Santos Toledo, Natasha Ferraz dos Campos Reis, Kleber Ribeiro, André Cronemberger-Andrade, Jeronimo Nunes Rugani, Beatriz Helena Pizarro De Lorenzo, Ronni Rômulo Novaes e Brito, Rodrigo Pedro Soares, Ana Claudia Torrecilhas, Patricia Xander   +11 more
doaj   +1 more source

Autophagic Induction Greatly Enhances Leishmania major Intracellular Survival Compared to Leishmania amazonensis in CBA/j-Infected Macrophages

Frontiers in Microbiology, 2018
CBA mouse macrophages control Leishmania major infection yet are permissive to Leishmania amazonensis. Few studies have been conducted to assess the role played by autophagy in Leishmania infection.
Beatriz R. S. Dias, Carina S. de Souza, Niara de Jesus Almeida, José G. B. Lima, Kiyoshi F. Fukutani, Thiale B. S. dos Santos, Jaqueline França-Cost, Jaqueline França-Cost, Claudia I. Brodskyn, Juliana P. B. de Menezes, Maria I. Colombo, Patricia S. T. Veras   +11 more
doaj   +1 more source

Cell migration induced by Leishmania (Leishmania) amazonensis, Leishmania (Leishmania) major and Leishmania (Viannia) braziliensis into the peritoneal cavity of BALB/c mice

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
In American cutaneous leishmaniasis, the initial infection phase is characterized by recruitment of neutrophils and monocytes. The migration of these cells in response to the presence of Leishmania in the peritoneum of affected animals remains unclear ...
DT Wakimoto, KV Gaspareto, TGV Silveira, MVC Lonardoni, SMA Aristides   +4 more
doaj   +1 more source

Leishmaniasis transmission biology: Role of Promastigote Secretory Gel as a transmission determinant [PDF]

Leishmaniasis is a complex vector-borne disease caused by Leishmania sp. (Kinetoplastida: Trypanosomatidae) and is transmitted by female sand flies (Diptera: Psychodidae).
Martin Sainz de la Maza, O
core   +1 more source

Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8 [PDF]

, 2013
Cysteine protease B is considered crucial for the survival and infectivity of the Leishmania in its human host. Several microorganism pathogens bind to the heparin-like glycosaminoglycans chains of proteoglycans at host-cell surface to promote their ...
Gesteira, Tarsis F., Juliano, Luiz, Tersariol, Ivarne L.S., Westrop, Gareth, Almeida, Paulo C, Souza, Gerson A., Judice, W.A.S., Sansevero, Thiago M., Sanderson, Sanya J, Coombs, Graham, Manfredi, Marcella A, Shida, Claudio S.   +11 more
core   +2 more sources

Comparative two-dimensional gel electrophoresis maps for promastigotes of Leishmania amazonensis and Leishmania major

Brazilian Journal of Infectious Diseases
The outcome of Leishmania infections is determined by both the parasite species and the host genetic makeup. While much has been learned regarding immune responses to this parasite, our knowledge on parasite-derived factors is limited.
Reynolds K. B. Brobey, Fang C. Mei, Xiaodong Cheng, Lynn Soong   +3 more
doaj   +1 more source