Results 61 to 70 of about 10,337 (219)

Nano‐Encapsulated Cinnamomum cassia Essential Oil in Combination With Fluconazole Exhibits Synergistic Activity Against Fluconazole‐Resistant Nakaseomyces glabratus and Pichia kudriavzevii

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Nano‐encapsulated Cinnamomum cassia essential oil (nano‐CC‐EO) showed in vitro antifungal activity against fluconazole‐resistant Nakaseomyces glabratus and Pichia kudriavzevii clinical isolates. Checkerboard assays revealed synergistic or additive interactions between nano‐CC‐EO and fluconazole in several isolates, without evidence of antagonism. These
Mehrdad Seifi, Mohammad Ali Esfandiary, Negar Hemmati, Javad Malakootikhah, Donya Nikaein, Ali Reza Khosravi   +5 more
wiley   +1 more source

The use of kDNA minicircle subclass relative abundance to differentiate between Leishmania (L.) infantum and Leishmania (L.) amazonensis

Parasites & Vectors, 2017
Background Leishmaniasis is a neglected disease caused by many Leishmania species, belonging to subgenera Leishmania (Leishmania) and Leishmania (Viannia).
Marcello Ceccarelli, Luca Galluzzi, Aurora Diotallevi, Francesca Andreoni, Hailie Fowler, Christine Petersen, Fabrizio Vitale, Mauro Magnani   +7 more
doaj   +1 more source

Axenic cultivation and characterization of Leishmania mexicana amastigote-like forms [PDF]

, 1992
A new method is described which has made possible the long-term axenic cultivation of Leishmania mexicana amastigote-like forms in Schneider's Drosophila medium supplemented with 20% (v/v) foetal calf serum.
Coombs, G H, Robertson, C D, Tetley, L, Bates, P A   +3 more
core  

T helper1/T helper2 cells and resistance/susceptibility to Leishmania infection : is this paradigm still relevant?

, 2012
Work in large part on Leishmania major in the 1980s identified two distinct apparently counter-regulatory CD4 T cell populations, T helper (h)1 and Th2, that controlled resistance/susceptibility to infection respectively.
Brombacher, F., James eAlexander, Frank Brombacher, Frank eBrombacher, Alexander, J., James Alexander   +5 more
core   +1 more source

Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review

Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.
This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
Maria Eduarda da Veiga Oliveira, Ellen Dyminski Parente Ribeiro, Otávio Henrique Pradi Guenther, Fernanda Tomiotto‐Pellissier   +3 more
wiley   +1 more source

Characterization of an extracellular serine protease ofLeishmania (Leishmania) amazonensis

Parasitology, 2005
A serine protease was purified 942-fold from culture supernatant ofL. amazonensispromastigotes using (NH4)2SO4precipitation followed by affinity chromatography on aprotinin-agarose and continuous elution electrophoresis by Prep Cell, yielding a total recovery of 61%.
R E, Silva-Lopez, M G Pinto, Coelho, S G, De Simone   +2 more
openaire   +2 more sources

Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient—A Case Report

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT HIV‐associated Immune Reconstitution Inflammatory Syndrome (IRIS) may significantly alter the immunopathological presentation of American Tegumentary Leishmaniasis (ATL), occasionally causing paradoxical clinical exacerbations. We report the long‐term follow‐up of a 39‐year‐old female coinfected with HIV and disseminated mucocutaneous ...
Marilia Brasil Xavier, Claudia Maria de Castro Gomes, Rita Catarina Medeiros Sousa, Edna Aoba Yassui Ishikawa, Elza Baía de Brito, Silvia Ferreira Rodrigues Müller, Lucas dos Santos Fontes, João Augusto Gomes de Souza Monteiro de Brito, Larissa dos Santos Alcantara, Carlos Eduardo Pereira Corbett   +9 more
wiley   +1 more source

Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT Mitogen‐activated protein kinases (MAPKs) are intracellular signalling proteins that modulate several cellular processes, such as proliferation, cytokine production and survival. Like humans, dogs may exhibit changes in MAPK signalling under pathological conditions.
Francini Neves Ribeiro, Fernanda Nazaré Morgado, Renato Porrozzi   +2 more
wiley   +1 more source

In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. Currently available treatments require long-term use and have serious side effects, necessitating the development of new
Carlos Eduardo Sampaio Guedes, Beatriz Rocha Simões Dias, Antonio Luis de Oliveira Almeida Petersen, Kercia Pinheiro Cruz, Niara de Jesus Almeida, Daniela Rodrigues Andrade, Juliana Perrone Bezerra de Menezes, Valéria de Matos Borges, Patricia Sampaio Tavares Veras   +8 more
doaj   +1 more source

Inoculation of the Leishmania infantum HSP70-II Null Mutant Induces Long-Term Protection against L. amazonensis Infection in BALB/c Mice

Microorganisms, 2021
Leishmania amazonensis parasites are etiological agents of cutaneous leishmaniasis in the New World. BALB/c mice are highly susceptible to L. amazonensis challenge due to their inability to mount parasite-dependent IFN-γ-mediated responses.
Manuel Soto, Laura Ramírez, José Carlos Solana, Emma C. L. Cook, Elena Hernández-García, José María Requena, Salvador Iborra   +6 more
doaj   +1 more source