Results 21 to 30 of about 35,037 (252)

Postoperative Late-Onset Endophthalmitis Caused by Leishmania donovani: A Case Report

Case Reports in Ophthalmology, 2018
Leishmania donovani is a human blood parasite that belongs to the genus Leishmania. We would like to present a case of late Leishmania donovani endophthalmitis in one eye of a patient that underwent simultaneous bilateral grade 3 cataract surgery.
Bojan Kozomara, Ernesta Potkonjak, Ratimir Lazic, Sanja Savicic, Nikica Gabric   +4 more
doaj   +1 more source

Leishmania donovani Exploits Tunneling Nanotubes for Dissemination and Propagation of B Cell Activation

Microbiology Spectrum, 2023
Polyclonal B cell activation and the resulting hypergammaglobulinemia are a detrimental consequence of visceral leishmaniasis (VL); however, the mechanisms underlying this excessive production of nonprotective antibodies are still poorly understood. Here,
Tanja Stögerer, Sasha Silva-Barrios, Liseth Carmona-Pérez, Sharada Swaminathan, Linh Thuy Mai, Louis-Philippe Leroux, Maritza Jaramillo, Albert Descoteaux, Simona Stäger   +8 more
doaj   +1 more source

Analysis by RNA-seq of transcriptomic changes elicited by heat shock in Leishmania major [PDF]

, 2019
Besides their medical relevance, Leishmania is an adequate model for studying post-transcriptional mechanisms of gene expression. In this microorganism, mRNA degradation/stabilization mechanisms together with translational control and post-translational ...
Aguado, Begoña, Corvo, Laura, Lombraña, Rodrigo, Rastrojo, Alberto, Requena, Jose M., Solana, Jose C.   +5 more
core   +2 more sources

Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

Parasites & Vectors, 2015
Background Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L.
Iva Rohousova, Dalit Talmi-Frank, Tatiana Kostalova, Nikola Polanska, Tereza Lestinova, Aysheshm Kassahun, Daniel Yasur-Landau, Carla Maia, Roni King, Jan Votypka, Charles L. Jaffe, Alon Warburg, Asrat Hailu, Petr Volf, Gad Baneth   +14 more
doaj   +1 more source

The in vitro leishmanicidal activity of hexadecylphosphocholine (miltefosine) against four medically relevant Leishmania species of Brazil

Memorias do Instituto Oswaldo Cruz, 2011
The in vitro leishmanicidal activity of miltefosine® (Zentaris GmbH) was assessed against four medically relevant Leishmania species of Brazil: Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, Leishmania (Viannia) guyanensis and ...
Eliane de Morais-Teixeira, Quesia Souza Damasceno, Mariana Kolos Galuppo, Alvaro José Romanha, Ana Rabello   +4 more
doaj   +1 more source

Development of a LAMP assay for detection of Leishmania infantum infection in dogs using conjunctival swab samples [PDF]

, 2015
Background: Leishmania infantum infections in dogs play a crucial role in the transmission of pathogens causing visceral leishmaniasis to humans in the Gansu province, northwest China. To be able to control zoonotic transmission of the parasite to humans,
A Moshfe, A Nasereddin, AF Koutinas, CH Gao, Chun-hua Gao, D Otranto, D Strauss-Ayali, Dan Ding, Dietmar Steverding, ER Adams, F Dantas-Torres, Feng Shi, G Schönian, H Kaneko, H Takagi, J Alvar, J Dereure, JM Lawrie, Jun-yun Wang, JY Wang, JY Wang, JY Wang, K Stuart, L Chamaillé, L He, L Solano-Gallego, LL Poon, LS Leontides, M Chaouch, M Gramiccia, M Paiva Cavalcanti de, MG Khan, N Chargui, N Kuboki, N Singh, P Ciaramella, RS Leite, S Reale, SA Ferreira, T Muccio Di, T Notomi, UG Lopes, WP Kennedy, X Ni, Xia Wang, Y Fichoux le, Y Mori, YM Gomes, Yue-tao Yang   +48 more
core   +1 more source

New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]

, 2015
Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Alonso-Padilla, Julio, Alvarez, Emilio, Bardera, Ana I., Barroso, Vanessa, Brown, James R., Cantizani, Juan, Colmenarejo, Gonzalo, Cotillo, Ignacio, de Dios-Anton, Francisco, Drewry, David H., Fiandor, Jose M., Gray, David W., Julio Martin, J., Kessler, Albane, Kumar, Vinod, Navarro, Miguel, Peña, Imanol, Pilar Manzano, M., Rodriguez, Ana, Roquero, Irene, Sherstnev, Alexander   +20 more
core   +3 more sources

Prevalence of Leishmania species among patients with cutaneous leishmaniasis in Qassim province of Saudi Arabia

BMC Public Health, 2019
Background Leishmaniasis is a parasitic infection endemic in more than ninety countries of the world. The cutaneous leishmaniasis (CL) is a most common form of leishmaniasis and it remains to be a major public health issue in Saudi Arabia. This study was
Zafar Rasheed, Ahmed A. Ahmed, Tarek Salem, Mohammed S. Al-Dhubaibi, Ahmad A. Al Robaee, Abdullateef A. Alzolibani   +5 more
doaj   +1 more source

Guanylate Binding Proteins Restrict Leishmania donovani Growth in Nonphagocytic Cells Independent of Parasitophorous Vacuolar Targeting

mBio, 2020
Interferon (IFN)-inducible guanylate binding proteins (GBPs) play important roles in host defense against many intracellular pathogens that reside within pathogen-containing vacuoles (PVs).
Arun Kumar Haldar, Utsav Nigam, Masahiro Yamamoto, Jörn Coers, Neena Goyal   +4 more
doaj   +1 more source

Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling [PDF]

, 2018
Cellular activation in trans by interferons, cytokines and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with
Andrews, Paul S., Beattie, Lynette, Hoehme, Stefan, Kaye, Paul M., Moore, John W. J., Moyo, Daniel, Sampson, Adam T., Sawtell, Amy, Timmis, Jon   +8 more
core   +5 more sources