Results 41 to 50 of about 80,278 (299)
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia
Parasites & Vectors, 2015 Background Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L.
Iva Rohousova +14 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2011 The in vitro leishmanicidal activity of miltefosine® (Zentaris GmbH) was assessed against four medically relevant Leishmania species of Brazil: Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, Leishmania (Viannia) guyanensis and ...
Eliane de Morais-Teixeira +4 more
doaj +1 more source
The metabolism of Leishmania donovani in culture [PDF]
Biochemical Journal, 1954 Lei8hnmnia donovani, the organism causing visceral leishmaniasis, is a small, round or ovoid body measuring 2-5 g. in diameter, which occurs exclusively within cells of the reticulo-endothelial system of its mammalian host. In culture, or in the insect vector, the parasite exists in a flagellate leptomonad form. In the case of L. tropica in culture, it
J. D. Fulton, L. P. Joyner, S. Crowther
openaire +3 more sources
Microbiology Spectrum, 2023 Polyclonal B cell activation and the resulting hypergammaglobulinemia are a detrimental consequence of visceral leishmaniasis (VL); however, the mechanisms underlying this excessive production of nonprotective antibodies are still poorly understood. Here,
Tanja Stögerer +8 more
doaj +1 more source
mBio, 2017 Aneuploidy is usually deleterious in multicellular organisms but appears to be tolerated and potentially beneficial in unicellular organisms, including pathogens. Leishmania, a major protozoan parasite, is emerging as a new model for aneuploidy, since in
F. Dumetz +19 more
semanticscholar +1 more source
Analysis by RNA-seq of transcriptomic changes elicited by heat shock in Leishmania major [PDF]
, 2019 Besides their medical relevance, Leishmania is an adequate model for studying post-transcriptional mechanisms of gene expression. In this microorganism, mRNA degradation/stabilization mechanisms together with translational control and post-translational ...
Aguado, Begoña +5 more
core +2 more sources
In vitro activity and mode of action of phenolic compounds on Leishmania donovani
PLoS Neglected Tropical Diseases, 2019 Background Leishmaniasis is a disease caused by the protozoan parasite, Leishmania. The disease remains a global threat to public health requiring effective chemotherapy for control and treatment.
C. Antwi +3 more
semanticscholar +1 more source
Detection of Leishmania DNA in wild foxes and associated ticks in Patagonia, Argentina, 2000 km south of its known distribution area [PDF]
, 2016 Indexación: Web of Science; PubMedBackground: Zoonotic Visceral Leishmaniasis (ZVL) is a vector-borne disease affecting humans and other mammals and caused by the protozoan parasite Leishmania (Leishmania) infantum (syn. L.
Ferroglio, Ezio +6 more
core +4 more sources
BMC Public Health, 2019 Background Leishmaniasis is a parasitic infection endemic in more than ninety countries of the world. The cutaneous leishmaniasis (CL) is a most common form of leishmaniasis and it remains to be a major public health issue in Saudi Arabia. This study was
Zafar Rasheed +5 more
doaj +1 more source
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]
, 2015 Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Alonso-Padilla, Julio +20 more
core +3 more sources