Results 81 to 90 of about 35,225 (252)

Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence. [PDF]

, 2011
Due to unacceptably high mortality with pentavalent antimonials, Médecins Sans Frontières in 2006 began using liposomal amphotericin B (AmBisome) for visceral leishmaniasis (VL) patients in Ethiopia who were severely ill or positive for human ...
Aderie, Endashaw Mengistu, Chane, Solomon, Collin, Simon M, Davidson, Robert N, Piening, Turid, Ritmeijer, Koert, ter Horst, Rachel   +6 more
core   +2 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Glutathione and the redox control system trypanothione/trypanothione reductase are involved in the protection of Leishmania spp. against nitrosothiol-induced cytotoxicity

Brazilian Journal of Medical and Biological Research, 2006
Glutathione is the major intracellular antioxidant thiol protecting mammalian cells against oxidative stress induced by oxygen- and nitrogen-derived reactive species.
P.R.T. Romão, J. Tovar, S.G. Fonseca, R.H. Moraes, A.K. Cruz, J.S. Hothersall, A.A. Noronha-Dutra, S.H. Ferreira, F.Q. Cunha   +8 more
doaj   +1 more source

A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia. [PDF]

, 2008
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and famine-stricken area.
Boelaert, M, Dujardin, J C, Jacquet, D, Marlet, M V L, Quispe, K W, Wuillaume, F   +5 more
core   +1 more source

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

, 2010
OBJECTIVE: Elevated serum levels of the acute-phase protein serum amyloid A (SAA) are a marker for active rheumatoid arthritis (RA), and SAA can also be found in the tissues of patients with active RA.
Björkman, Lena, Bylund, Johan, Dahlgren, Claes, Karlsson, Anna, Raynes, John G, Shah, Chandrabala   +5 more
core   +1 more source

Evaluation of antigens for the serodiagnosis of kala-azar and oriental sores by means of the indirect immunofluorescence antibody test (IFAT) [PDF]

, 1981
Antigens and corresponding sera were collected from travellers with leishmaniasis returning to Germany from different endemic areas of the old world. The antigenicity of these Leishmania strains, which were maintained in Syrian hamsters, was compared by ...
A. Zuckermann, E. C. Hedge, E. Mannweiler, F. Falkner v. Sonnenburg, G. Piekarski, G. Weiland, Gh. H. Endrissian, H. E. Krampitz, H. E. Krampitz, H. E. Krampitz, J. J. Shaw, J. Ranque, L. Prüfer, M. Lopez-Brea, N. Beforouz, R. S. Bray, R. S. Bray, R. S. Bray, T. I. Aljeboori, Th. Löscher   +19 more
core   +1 more source

A Forgotten Foe Returns: The Diagnostic Odyssey of Kala‐Azar Masquerading as Myelodysplastic Syndrome in a Post‐Elimination Era

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT We report a diagnostically complex case of visceral leishmaniasis (Kala‐azar) in a 73‐year‐old male from a country where the disease was eliminated in 2023. The patient presented with a 2‐month history of low‐grade fever, fatigue, progressive skin hyperpigmentation over 2 years, and hepatosplenomegaly.
Sumaya Khan Mifty, Saiful Islam Chowdhury, Tahmidur Rahman, Tanveer Al Razi Khan, Swagota Roy, Faiza Ahmmed, Md. Sabbir Hossain, Ibrahim Khalil   +7 more
wiley   +1 more source

Identification of potential inhibitor against Leishmania donovani mitochondrial DNA primase through in-silico and in vitro drug repurposing approaches

Scientific Reports
Leishmania donovani is the causal organism of leishmaniasis with critical health implications affecting about 12 million people around the globe. Due to less efficacy, adverse side effects, and resistance, the available therapeutic molecules fail to ...
Mitul Nath, Deep Bhowmik, Satabdi Saha, Rajat Nandi, Diwakar Kumar   +4 more
doaj   +1 more source

Global genome diversity of the Leishmania donovani complex

eLife, 2020
Protozoan parasites of the Leishmania donovani complex – L. donovani and L. infantum – cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome-wide global study, with 151 cultured field isolates representing most of the ...
Susanne U Franssen, Caroline Durrant, Olivia Stark, Bettina Moser, Tim Downing, Hideo Imamura, Jean-Claude Dujardin, Mandy J Sanders, Isabel Mauricio, Michael A Miles, Lionel F Schnur, Charles L Jaffe, Abdelmajeed Nasereddin, Henk Schallig, Matthew Yeo, Tapan Bhattacharyya, Mohammad Z Alam, Matthew Berriman, Thierry Wirth, Gabriele Schönian, James A Cotton   +20 more
doaj   +1 more source

Insights into Leishmania donovani potassium channel family and their biological functions [PDF]

, 2023
Anindita Paul, Shubham Sunil Chumbale, Anjana Lakra, Vijay Kumar, Dhanashri Sudam Alhat, Sushma Singh   +5 more
openalex   +1 more source