Results 151 to 160 of about 13,685 (176)

Leishmania (L.) amazonensis: Fusion between parasitophorous vacuoles in infected bone-marrow derived mouse macrophages

Experimental Parasitology, 2008
[Leishmania(L.)] amazonensis amastigotes reside in macrophages within spacious parasitophorous vacuoles (PVs) which may contain numerous parasites. After sporadic fusion events were detected by time-lapse cinemicrography, PV fusion was examined in two different models. In single infections, it was inferred from the reduction in PV numbers per cell.
Real, F. UNIFESP, Pouchelet, M., Rabinovitch, M. UNIFESP   +2 more
openaire   +3 more sources

USING KDNA MINICIRCLE SUBCLASS RELATIVE ABUNDANCE TO DIFFERENTIATE LEISHMANIA (L.) INFANTUM FROM LEISHMANIA (L.) AMAZONENSIS

2017
1 Background Leishmaniasis is a neglected disease caused by many Leishmania species, belonging to subgenera Leishmania (Leishmania) and Leishmania (Viannia). Several qPCR-based molecular diagnostic approaches have been reported for detection and quantification of Leishmania species. Many of these approaches use the kinetoplast DNA (kDNA) minicircles as
Marcello Ceccarelli, Luca Galluzzi, Aurora Diotallevi, Francesca Andreoni, Hailie Fowler, Christine Petersen, Fabrizio Vitale, Mauro Magnani   +7 more
openaire   +1 more source

Melatonin attenuatesLeishmania (L.) amazonensisinfection by modulating arginine metabolism

Journal of Pineal Research, 2015
AbstractAcute inflammatory responses induced by bacteria or fungi block nocturnal melatonin synthesis by rodent pineal glands. Here, we showLeishmaniainfection does not impair daily melatonin rhythm in hamsters. Remarkably, the attenuated parasite burden and lesion progression in hamsters infected at nighttime was impaired by blockage of melatonin ...
Maria Fernanda, Laranjeira-Silva, Ricardo A, Zampieri, Sandra M, Muxel, Lucile Maria, Floeter-Winter, Regina P, Markus   +4 more
openaire   +2 more sources

N-acetyl-l-cysteine reduces the parasitism of BALB/c mice infected with Leishmania amazonensis

Parasitology Research, 2007
Leishmania amazonensis infection leads to progressive diseases in a majority of inbred strains of mice. Glutathione (GSH) participates in a large number of cellular phenomena and seems to be essential for several immune functions, including host defense during leishmaniasis. In this study, we evaluated the effects of N-acetyl-L: -cysteine (NAC), as GSH
Marta Chagas, Monteiro, Fúlvia Carina Souza, Marques, Renê Darela, Blazius, Onilda, Santos da Silva, Fernando, de Queiroz Cunha, Diana Bittencourt, Bento, Pedro Roosevelt, Torres Romão   +6 more
openaire   +2 more sources

Cloning and characterisation of a cysteine proteinase gene expressed in amastigotes of Leishmania (L.) amazonensis

International Journal for Parasitology, 2003
The present study describes the cloning and characterisation of a gene encoding a cysteine proteinase isoform, Llacys1, expressed in amastigote forms of Leishmania (L.) amazonensis. Recombinant clones containing the Llacys1 gene were isolated from genomic DNA by PCR amplification and screening of an amastigote cDNA library.
Fernanda, Lasakosvitsch, Luciana Girotto, Gentil, Márcia Regina Machado, dos Santos, José Franco, da Silveira, Clara Lúcia, Barbiéri   +4 more
openaire   +2 more sources

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce, Lorenzo Cohen, Karen M Mustian   +2 more
exaly  

Effect of Copaifera reticulata on amastigote forms of Leishmania (L.) amazonensis

Planta Medica, 2008
AO dos Santos, T Ueda-Nakamura, BPD Filho, VF da Veiga Jr, AC Pinto, CV Nakamura   +5 more
openaire   +1 more source

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

Ca-A Cancer Journal for Clinicians, 2017
Cynthia Morata-Tarifa, Joyce M Slingerland   +1 more
exaly  

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

Ca-A Cancer Journal for Clinicians, 2020
Aaron J Grossberg, William L Hwang, Anirban Maitra   +2 more
exaly  

Oral complications of cancer and cancer therapy

Ca-A Cancer Journal for Clinicians, 2012
Joel B Epstein, Rene-Jean Bensadoun, Andrei Barasch   +2 more
exaly