Results 121 to 130 of about 66,437 (256)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

ITS1 PCR-RFLP Diagnosis and Characterization of Leishmania in Clinical Samples and Strains from Cases of Human Cutaneous Leishmaniasis in States of the Mexican Southeast

Interdisciplinary Perspectives on Infectious Diseases, 2014
American cutaneous leishmaniasis includes a spectrum of clinical forms localized cutaneous, diffuse cutaneous, and mucocutaneous leishmaniasis which can be caused by different strains of Leishmania belonging to the L. mexicana or L.
Amalia Monroy-Ostria, Abedelmajeed Nasereddin, Victor M. Monteon, Carmen Guzmán-Bracho, Charles L. Jaffe   +4 more
doaj   +1 more source

Phlebotomine fauna (Diptera: Psychodidae) of an American cutaneous leishmaniasis endemic area in the state of Mato Grosso do Sul, Brazil

Memorias do Instituto Oswaldo Cruz, 2009
The occurrence of an outbreak of cutaneous leishmaniasis associated with Leishmania (Leishmania) amazonensis in the municipality of Bela Vista, state of Mato Grosso do Sul, Brazil, and the absence of information on its vectors in this area led the ...
Maria Elizabeth C Dorval, Geucira Cristaldo, Hilda Carlos da Rocha, Tulia Peixoto Alves, Murilo Andrade Alves, Elisa Teruya Oshiro, Alessandra Gutierrez de Oliveira, Reginaldo Peçanha Brazil, Eunice Aparecida Bianchi Galati, Rivaldo Venâncio da Cunha   +9 more
doaj   +1 more source

2-Substituted quinoline alkaloids as potential antileishmanial drugs [PDF]

, 1993
Ten 2-substituted quinoline alkaloids isolated from a plant used for treatment of New World cutaneous leishmaniasis have antileishmanial in vitro activities against the extracellular forms of Leishmania spp.
Barrios, A.A., Bruneton, J., Cavé, A., Fournet, Alain, Hocquemiller, R., Munoz, V.   +5 more
core   +1 more source

Eco-epidemiological aspects, natural detection and molecular identification of Leishmania spp. in Lutzomyia reburra, Lutzomyia barrettoi majuscula and Lutzomyia trapidoi

Biomédica: revista del Instituto Nacional de Salud, 2017
Introduction: The province of Pichincha in Ecuador is an endemic area of cutaneous leishmaniasis, where anthropophilic sand flies with natural infection by Leishmania, have been reported as vectors.
Jazzmín Arrivillaga-Henríquez, Sandra Enríquez, Vanessa Romero, Gustavo Echeverría, Jorge Pérez-Barrera, Ana Poveda, Juan-Carlos Navarro, Alon Warburg, Washington Benítez   +8 more
doaj   +1 more source

Estudo epidemiológico das leishmanioses em área de turismo ambiental e ecoturismo, Estado de Mato Grosso do Sul, 2006-2007 [PDF]

, 2009
The aims of this study were to carry out a serological survey of canine leishmaniasis and identify the phlebotomine fauna in the urban area of Bonito, Mato Grosso do Sul.
ANDRADE, Ana Rachel Oliveira de, AQUINO, Ricardo Braga, ARRUDA, Carla Cardozo Pinto de, GALATI, Eunice Aparecida Bianchi, NUNES, Vânia Lúcia Brandão, ROCCA, Maria Elizabeth Gizi, SANTOS, Mirella Ferreira da Cunha   +6 more
core   +3 more sources

Characterization of an extracellular serine protease ofLeishmania (Leishmania) amazonensis

Parasitology, 2005
A serine protease was purified 942-fold from culture supernatant ofL. amazonensispromastigotes using (NH4)2SO4precipitation followed by affinity chromatography on aprotinin-agarose and continuous elution electrophoresis by Prep Cell, yielding a total recovery of 61%.
R E, Silva-Lopez, M G Pinto, Coelho, S G, De Simone   +2 more
openaire   +2 more sources

In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. Currently available treatments require long-term use and have serious side effects, necessitating the development of new
Carlos Eduardo Sampaio Guedes, Beatriz Rocha Simões Dias, Antonio Luis de Oliveira Almeida Petersen, Kercia Pinheiro Cruz, Niara de Jesus Almeida, Daniela Rodrigues Andrade, Juliana Perrone Bezerra de Menezes, Valéria de Matos Borges, Patricia Sampaio Tavares Veras   +8 more
doaj   +1 more source

Evidence for regulated expression of Telomeric Repeat-containing RNAs (TERRA) in parasitic trypanosomatids [PDF]

, 2017
The Telomeric Repeat-containing RNAs (TERRA) participate in the homeostasis of telomeres in higher eukaryotes. Here, we investigated the expression of TERRA in Leishmania spp.
Damasceno, Jeziel D., Silva, Gabriel L.A., Tosi, Luiz R.O., Tschudi, Christian   +3 more
core   +1 more source

Further observations on clinical, histopathological, and immunological features of borderline disseminated cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis.

Memórias do Instituto Oswaldo Cruz, 2005
Leishmania (Leishmania) amazonensis has for some time been considered as the causative agent of two distinct forms of American cutaneous leishmaniasis (ACL): localized cutaneous leishmaniasis (LCL), and anergic diffuse cutaneous leishmaniasis (ADCL ...
F. Silveira, R. Lainson, C. Corbett
semanticscholar   +1 more source