Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]
Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris +55 more
core +5 more sources
The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly Vector
The life cycle of the Leishmania parasite in the sand fly vector involves differentiation into several distinctive forms, each thought to represent an adaptation to specific microenvironments in the midgut of the fly.
Ehud Inbar +5 more
semanticscholar +1 more source
Detection and identification of Leishmania species within naturally infected sand flies in the Andean areas of Ecuador by a polymerase chain reaction [PDF]
The surveillance of prevalent Leishmania and sand fly species in endemic areas is important for prediction of the risk and expansion of leishmaniasis. In this study, we developed a polymerase chain reaction (PCR)-based method for detection of Leishmania ...
Barroso, Paola Andrea +11 more
core +1 more source
Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E +19 more
core +3 more sources
Cyclic nucleotide specific phosphodiesterases of Leishmania major [PDF]
Abstract Background Leishmania represent a complex of important human pathogens that belong to the systematic order of the kinetoplastida. They are transmitted between their human and mammalian hosts by different bloodsucking sandfly vectors.
Johner, Andrea +4 more
openaire +4 more sources
Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran
The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by Leishmania major).
Bibi Razieh Hosseini Farash +10 more
doaj +1 more source
Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world [PDF]
[No abstract ...
A Berry +108 more
core +2 more sources
Homologous recombination (HR) has an intimate relationship with genome replication, both during repair of DNA lesions that might prevent DNA synthesis and in tackling stalls to the replication fork.
J. Damasceno +6 more
semanticscholar +1 more source
: Objectives: Cutaneous leishmaniasis (CL) in Asia, Northern, and Sub-Saharan Africa is mainly caused by Leishmania major and Leishmania tropica. We describe and evaluate the treatment outcome of CL among travelers and migrants in Europe.
Hedvig Glans +14 more
doaj +1 more source
Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]
Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM +4 more
core +1 more source

