Results 81 to 90 of about 13,441 (240)

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays [PDF]

, 2018
The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an estimated 1 million new cases each year. Current treatments are toxic, expensive, difficult to administer, and resistance to them is emerging.
Berry, SL, Hameed, H, Horrocks, P, Maciej-Hulme, ML, Price, HP, Saif Abou-Akkada, S, Thomason, A   +6 more
core   +7 more sources

Leishmania major Infection in Synanthropic Rodents: Evidence for the Urbanization of Zoonotic Cutaneous Leishmaniasis (ZCL) in Southern Iran

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2024, Issue 1, 2024.
Cutaneous leishmaniasis is of particular importance in southern Iran. This study aimed to investigate the infection of rodents with Leishmania major in an urban area of Fars Province, located in southern Iran. Rodents were trapped and samples from the liver, spleen, and skin were collected.
Saeed Shahabi, Kourosh Azizi, Qasem Asgari, Bahador Sarkari, Marco Di Luca   +4 more
wiley   +1 more source

Cloning and expression of codon-optimized recombinant darbepoetin alfa in Leishmania tarentolae T7-TR [PDF]

, 2016
Darbepoetin alfa is an engineered and hyperglycosylated analog of recombinant human erythropoietin (EPO) which is used as a drug in treating anemia in patients with chronic kidney failure and cancer.
Fard-Esfahani, P., Golavar, R., Khajeniazi, S., Kianmehr, A., Mahrooz, A., Mostafavi, S.S., Oladnabi, M., Omidinia, E., Rouintan, M.   +8 more
core   +1 more source

Using Biotic Interaction Networks for Prediction in Biodiversity and Emerging Diseases [PDF]

, 2008
Networks offer a powerful tool for understanding and visualizing inter-species interactions within an ecology. Previously considered examples, such as trophic networks, are just representations of experimentally observed direct interactions.
Autonoma México, Camila González-rosas, Carlos N. Ibarra-cerdeña, Christopher R. Stephens, Joaquin Giménez Heau, Victor Sánchez-cordero   +5 more
core   +2 more sources

Differential effects of paramomycin on ribosomes of Leishmania mexicana and Mammalian cells [PDF]

, 2010
Paromomycin, an aminoglycoside antibiotic having low mammalian cell toxicity, is one of the drugs currently used in the chemotherapy of cutaneous and visceral leishmaniasis.
Algranati, Israel David, Fernández, Marisa Mariel, Malchiodi, Emilio Luis   +2 more
core   +2 more sources

The variety of characters in PSL(2,C) [PDF]

Bol. Soc. Mat. Mexicana (3) 10 (2004), Special Issue, 221--237, 2003
We study some basic properties of the variety of characters in PSL(2,C) of a finitely generated group. In particular we give an interpretation of its points as characters of representations. We construct 3-manifolds whose variety of characters has arbitrarily many components that do not lift to SL(2,C).
arxiv  

Leishmania mexicana potential drug target

The FASEB Journal, 2012
We have been studying the Leishmania mexicana protein kinase Lmx‐MPK1. Lmx‐MPK1 is required for parasite viability in the host and represents a potential therapeutic target. We have been studying the interaction of the human p38 mitogen‐activated protein kinase (p38 MAPK) inhibitor, BIRB 796, with Lmx‐ MPK1.
John J. Siekierka, Aysenur Sayakci, Nina M. Goodey, Seema Patel, Tamara Kreiss   +4 more
openaire   +1 more source

Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation [PDF]

, 2016
Leishmania mexicana has a large family of cyclin-dependent kinases (CDKs) that reflect the complex interplay between cell cycle and life cycle progression.
Alvar, Ambit, Andenmatten, Banerjee, Branchini, Castanys-Muñoz, Cicenas, Cleghorn, Collins, Dacher, Efstathiou, Gomes, Goyal, Grant, Grant, Hammarton, Hassan, Jorda, Jullien, Jullien, Knapp, Lang, Lecoeur, Madeira da Silva, Maity, McLatchie, Misslitz, Morales, Ploubidou, Reichwald, Rogers, Talmi-Frank, Tu, Vasquez, Walker, Wang, Wang, Wiese, Williams, Řezníčková   +39 more
core   +2 more sources

Induced Bremsstrahlung by light in graphene [PDF]

Revista Mexicana de F\'isica 64, 132 (2018), 2018
We study the generation of an electromagnetic current in monolayer graphene immersed in a weak perpendicular magnetic field and radiated with linearly polarized monochromatic light. Such a current emits Bremsstrahlung radiation with the same amplitude above and below the plane of the sample, in the latter case consistent with the small amount of light ...
arxiv  

Electromagnetic quasinormal modes of five-dimensional topological black holes [PDF]

Revista Mexicana de Fisica 63 (2017) 541-548, 2018
We calculate exactly the QNF of the vector type and scalar type electromagnetic fields propagating on a family of five-dimensional topological black holes. To get a discrete spectrum of quasinormal frequencies for the scalar type electromagnetic field we find that it is necessary to change the boundary condition usually imposed at the asymptotic region.
arxiv