Immunity to Leishmania mexicana parasite [PDF]
Background: Cutaneous Leishmaniasis caused by the Leishmania mexicana complex is associated with unpleasant or disfiguring lesions, for which there only limited treatment options. The life cycle of L.
Ali, KSM
core
Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG [PDF]
Sand flies are the exclusive vectors of the protozoan parasite Leishmania, but the mechanism of transmission by fly bite has not been determined nor incorporated into experimental models of infection.
Bates, Paul A. +18 more
core +1 more source
Axenic cultivation and characterization of Leishmania mexicana amastigote-like forms [PDF]
A new method is described which has made possible the long-term axenic cultivation of Leishmania mexicana amastigote-like forms in Schneider's Drosophila medium supplemented with 20% (v/v) foetal calf serum.
Coombs, G H +3 more
core
"Leishmania infantum" : molecular analysis for identification of potential virulence factors and genes of diagnostic use [PDF]
Leishmania infantum is the causative agents of zoonotic visceral leishmaniasis, a fatal disease if left untreated. In Southern Europe, the number of HIV/Leishmania infantum co-infections is increasing and becomes an emerging concern for the public health.
Niederwieser, Igor
core +1 more source
Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections. [PDF]
In infected mammalian cells, Leishmania parasites reside within specialized compartments called parasitophorous vacuoles (LPVs). We have previously shown that Retro-2, a member of a novel class of small retrograde pathway inhibitors caused reduced LPV ...
Evan Craig +5 more
doaj +1 more source
Brain Involvement in Leishmaniasis
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas +2 more
wiley +1 more source
Leishmania infantum proteophosphoglycans regurgitated by the bite of its natural sand fly vector, Lutzomyia longipalpis, promote parasite establishment in mouse skin and skin-distant tissues [PDF]
We demonstrate that a proteophosphoglycan-rich gel secreted by Leishmania infantum inside the midgut of Lutzomyia longipalpis sand flies (promastigote secretory gel) is regurgitated along with an average dose of 500 L.
Müller, Ingrid +7 more
core +1 more source
Comportamiento de flagelados de la familia Trypanosomatidae en dos medios de cultivo modificados
Se reporta un medio de cultivo monofásico sólido (NNN modificado) y un medio monofásico líquido (RE I modificado) de gran utilidad para cultivos in vitro de flagelados de la Familia Trypanosomatidae.
Sofía Duque Beltrán +2 more
doaj +1 more source
Studies on immunology of Leishmania mexicana [PDF]
Leishmaniasis is a worldwide disease prevalent in many tropical and sub tropical countries. Treatment of Leishmaniasis by chemotherapy is not wholly effective and is usually accompanied by unpleasant side effects.
Rezvan, H, Rezvan, Hossein
core
Fez-se o registro, na Amazônia, do primeiro caso humano de infecção cutânea mista determinada por duas espécies distintas de Leishmania: a Leishmania braziliensis braziliensis e a Leishmania mexicana amazonensis.
F. T. Silveira +3 more
doaj +1 more source

