Results 71 to 80 of about 4,221 (205)

High Resolution Melting Analysis Targeting hsp70 as a Fast and Efficient Method for the Discrimination of Leishmania Species. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Protozoan parasites of the genus Leishmania cause a large spectrum of clinical manifestations known as Leishmaniases. These diseases are increasingly important public health problems in many countries both within and outside endemic regions ...
Ricardo Andrade Zampieri, Maria Fernanda Laranjeira-Silva, Sandra Marcia Muxel, Ana Carolina Stocco de Lima, Jeffrey Jon Shaw, Lucile Maria Floeter-Winter   +5 more
doaj   +1 more source

Mucocutaneous Leishmaniasis With Oral Involvement: A Case Report

Case Reports in Dentistry, Volume 2025, Issue 1, 2025.
The primary objective of the present study is the retrospective analysis of a clinical case of oral leishmaniasis treated at Parma Hospital and a review of the literature on mucosal leishmaniasis (ML) with oral cavity involvement. We report the case of a patient diagnosed in 2017 with mucocutaneous leishmaniasis who was referred to our clinic due to ...
Pierpaolo De Francesco, Paolo Vescovi, Claudio Feliciani, Roberta Iaria, Luigi Corcione, Ilaria Giovannacci, Vlaho Brailo   +6 more
wiley   +1 more source

Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]

, 2010
Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
Breitling, Rainer,, Brunker, Kirstyn, Jean-Claude Dujardin, Breitling Rainer, Dujardin, Jean-Claude, Dujardin, Jean Claude, Scheltema, R.A., Coombs, Graham H.,, Rijal, Suman,, Brunker Kirstyn, Coombs, Graham H, Dujardin, J.-C., Rijal, S., Kirstyn Brunker, Coombs Graham H., Coombs, Graham H., Dujardin, Jean-Claude,, Dujardin Jean-Claude, Watson, David G, Jankevics, Andris,, Jankevics Andris, Saskia Decuypere, Watson, D.G., t'Kindt, R., Kindt, Ruben t’,, Suman Rijal, t'Kindt, Ruben, t'Kindt Ruben, Watson David G., Breitling, Rainer, Brunker, K., Breitling, R., Brunker, Kirstyn,, Scheltema Richard A., Jankevics, A., Richard A Scheltema, Geary, T.G., Rijal Suman, Decuypere, S., Graham H. Coombs, Coombs, G.H., Andris Jankevics, Decuypere, Saskia, Scheltema, Richard A, Scheltema, Richard A., David G. Watson, Watson, David G., Richard A. Scheltema, Rainer Breitling, Decuypere Saskia, Jankevics, Andris, Decuypere, Saskia,, Watson, David G.,, David G Watson, 't Kindt, Ruben, Rijal, Suman, Ruben t'Kindt, Scheltema, Richard A.,, Graham H Coombs   +58 more
core   +1 more source

The principal reservoir host of cutaneous leishmaniasis in the urban areas of Manaus, Central Amazon of Brazil

Memorias do Instituto Oswaldo Cruz, 1981
Twenty one opossums (Didelphis marsupialis) from disturbed primary forest in the vicinity of Manaus, and seven from an isolated island of secondary vegetation within the city of Manaus, were examined for the presence of Leishmania.
Jorge R. Arias, Roberto D. Naiff
doaj   +1 more source

Unveiling the Interplay Between Dendritic Cells and Natural Killer Cells as Key Players in Leishmania Infection

Journal of Immunology Research, Volume 2025, Issue 1, 2025.
Leishmaniasis is a group of parasitic diseases whose etiological agent is the protozoa Leishmania. These diseases afflict impoverished populations in tropical and subtropical regions and affect wild and domestic animals. Canine leishmaniasis is a global disease mostly caused by L. infantum.
Ana Valério-Bolas, Mafalda Meunier, Armanda Rodrigues, Joana Palma-Marques, Rui Ferreira, Inês Cardoso, Lis Lobo, Marta Monteiro, Telmo Nunes, Ana Armada, Wilson T. Antunes, Graça Alexandre-Pires, Isabel Pereira da Fonseca, Gabriela Santos-Gomes, Rahul Shivahare   +14 more
wiley   +1 more source

Case of widespread and atypical cutaneous leishmaniasis in a young woman with breast cancer

Clinical Case Reports, Volume 12, Issue 8, August 2024.
Key Clinical Message Cutaneous leishmaniasis is caused by protozoan parasites of the genus leishmania. Atypical presentation and widespread progression of the lesions may be seen in an immunocompromised patient. We report a case of atypical and widespread cutaneous leishmaniasis in a young woman with breast cancer.
Fatemeh Mohaghegh, Fatemeh Mokhtari, Fereshteh Sherafat, Mohammad Shoushtarizadeh, Elham Tavousi Tabatabaei   +4 more
wiley   +1 more source

Potential of extracellular vesicles in the pathogenesis, diagnosis and therapy for parasitic diseases

Journal of Extracellular Vesicles, Volume 13, Issue 8, August 2024.
Abstract Parasitic diseases have a significant impact on human and animal health, representing a major hazard to the public and causing economic and health damage worldwide. Extracellular vesicles (EVs) have long been recognized as diagnostic and therapeutic tools but are now also known to be implicated in the natural history of parasitic diseases and ...
Ana Acacia Sá Pinheiro, Ana Claudia Torrecilhas, Bruno Solano de Freitas Souza, Fernanda Ferreira Cruz, Herbert Leonel de Matos Guedes, Tadeu Diniz Ramos, Miqueias Lopes‐Pacheco, Celso Caruso‐Neves, Patricia R. M. Rocco   +8 more
wiley   +1 more source

Assessment of PCR in the detection of Leishmania spp in experimentally infected individual phlebotomine sandflies (Diptera: Psychodidae: Phlebotominae)

Revista do Instituto de Medicina Tropical de São Paulo, 2002
DNA amplification by the polymerase chain reaction (PCR) was applied in the investigation of the presence of Leishmania (Kinetoplastida: Trypanosomatidae) parasites in single phlebotomine sandflies.
MICHALSKY Érika M., FORTES-DIAS Consuelo L., PIMENTA Paulo F.P., SECUNDINO Nágila F.C., DIAS Edelberto S.   +4 more
doaj  

Treatment of mucocutaneous leishmaniasis – A systematic review

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 6, Page 763-773, June 2024.
Summary Mucocutaneous leishmaniasis is a severe infectious disease, predominantly endemic in Central and South America and is characterized by granulomatous, destructive mucosal lesions in the oral, nasal, and pharyngeal cavities. It is caused by protozoa of the genus Leishmania spp. transmitted to humans by sandflies.
Theresa Fischer, Marcellus Fischer, Sibylle Schliemann, Peter Elsner   +3 more
wiley   +1 more source

Activity of anti-cancer protein kinase inhibitors against Leishmania spp. [PDF]

, 2014
OBJECTIVES: There is an urgent need to develop new and effective treatments for poverty-related neglected diseases. In light of the time required to bring a new drug to market and the cost involved (10-15 years, >1 billion US$), one approach to ...
Croft, Simon L, Sanderson, Lisa, Yardley, Vanessa   +2 more
core   +1 more source