Results 1 to 10 of about 122,780 (298)
Identification of a small molecule for enhancing lentiviral transduction of T cells
Molecular Therapy: Methods & Clinical Development, 2023 Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies.
Paulina Malach +10 more
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Lentivirus Gene Engineering Protocols [PDF]
British Journal of Cancer, 2004 Retroviruses including lentiviruses possess purposeful machinery to insert their genes into host cell chromosomes. Delivering genes of choice in retroviral particles allows their stable and possibly lifelong expression. Traditionally, murine leukaemia virus, an oncovirus but not lentivirus, has been the most studied virus and used for this ‘gene ...
openaire +2 more sources
Discovery and analysis of the first endogenous lentivirus [PDF]
Proceedings of the National Academy of Sciences, 2007 The lentiviruses are associated with a wide range of chronic diseases in mammals. These include immunodeficiencies (such as HIV/AIDS in humans), malignancies, and lymphatic and neurological disorders in primates, felids, and a variety of wild and domesticated ungulates.
Katzourakis, A +3 more
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Impact of Veterinary Vaccines on Human Health and Probable Challenges
Acta Veterinaria Eurasia, 2021 Md. Mehadi Hasan SOHAG +1 more
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Lentiviral-Mediated Transgene Expression Can Potentiate Intestinal Mesenchymal-Epithelial Signaling
Biological Procedures Online, 2009 Mesenchymal-epithelial signaling is essential for the development of many organs and is often disrupted in disease. In this study, we demonstrate the use of lentiviral-mediated transgene delivery as an effective approach for ectopic transgene expression ...
Kohn Aimee +3 more
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Gene therapy for the neurological manifestations in lysosomal storage disorders
Journal of Lipid Research, 2014 Over the past several years, considerable progress has been made in the development of gene therapy as a therapeutic strategy for a variety of inherited metabolic diseases, including neuropathic lysosomal storage disorders (LSDs).
Seng H. Cheng
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Global prevalence and risk factors of equine infectious anemia: A systematic review and meta-analysis [PDF]
Veterinary WorldBackground and Aim: Equine infectious anemia (EIA) is a lentiviral disease affecting members of the Equidae family, with global distribution and significant implications for animal health and biosecurity.
Lintang Winantya Firdausy +4 more
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Construction and Testing of orfA +/- FIV Reporter Viruses
Viruses, 2012 Single cycle reporter viruses that preserve the majority of the HIV-1 genome, long terminal repeat-promoted transcription and Rev-dependent structural protein expression are useful for investigating the viral life cycle.
Eric M. Poeschla +2 more
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Viruses, 2011 We developed a feline model of lentiviral cross-species transmission using a puma lentivirus (PLV or FIVPco) which infects domestic cats but does not cause disease.
Sue VandeWoude +4 more
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Viruses, 2012 Initiating combination antiretroviral therapy (ART) during acute HIV infection has been correlated with decreased viral set point and improved lymphocyte function.
Jonathan E. Fogle, Michelle M. Miller
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