Results 1 to 10 of about 172,662 (343)
Advances in Lentivirus Purification
Biotechnology Journal, 2020 AbstractLentiviral vectors (LVs) have been increasingly used as a tool for gene and cell therapies since they can stably integrate the genome in dividing and nondividing cells. LV production and purification processes have evolved substantially over the last decades.
Ana Sofia, Moreira +5 more
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Lentivirus production v1 [PDF]
, 2022 This protocol describes the production of lentiviruses to transduce HEK293T cells and has to be performed in a biosafety level 2 laboratory
Itika Saha +2 more
openalex +2 more sources
SARS-CoV-2 Neutralization Assay System using Pseudo-lentivirus
Indonesian Biomedical Journal, 2023 BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects humans' lower respiratory tracts and causes coronavirus disease-2019 (COVID-19).
Anastasia Armimi +9 more
doaj +1 more source
Lentivirus-mediated gene therapy for Fabry disease
Nature Communications, 2021 Enzyme and chaperone therapies are used to treat Fabry disease. Such treatments are expensive and require intrusive biweekly infusions; they are also not particularly efficacious.
Aneal Khan +23 more
semanticscholar +1 more source
Human Retrovirus Genomic RNA Packaging
Viruses, 2022 Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles.
Heather M. Hanson +3 more
doaj +1 more source
The Battle between Retroviruses and APOBEC3 Genes: Its Past and Present
Viruses, 2021 The APOBEC3 family of proteins in mammals consists of cellular cytosine deaminases and well-known restriction factors against retroviruses, including lentiviruses.
Keiya Uriu +3 more
doaj +1 more source
Journal of Visualized Experiments, 2009 RNA interference (RNAi) is a system of gene silencing in living cells. In RNAi, genes homologous in sequence to short interfering RNAs (siRNA) are silenced at the post-transcriptional state. Short hairpin RNAs, precursors to siRNA, can be expressed using lentivirus, allowing for RNAi in a variety of cell types.
Xiaoyin, Wang, Michael, McManus
openaire +2 more sources
Biotechnology and Bioengineering, 2021 A complex cellular cascade characterizes the pathophysiological response following spinal cord injury (SCI) limiting regeneration. Biomaterial and stem cell combination therapies together have shown synergistic effects, compared to the independent ...
A. J. Ciciriello +5 more
semanticscholar +1 more source
Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays [PDF]
Journal of Controlled Release, 2010 We employed fibrin hydrogel as a bioactive matrix for lentivirus mediated gene transfer. Fibrin-mediated gene transfer was highly efficient and exhibited strong dependence on fibrinogen concentration. Efficient gene transfer was achieved with fibrinogen concentration between 3.75 and 7.5mg/ml.
Shruti D, Raut +3 more
openaire +2 more sources