Results 11 to 20 of about 173,548 (215)
An endogenous lentivirus in the germline of a rodent [PDF]
Retrovirology, 2022 Lentiviruses (genus Lentivirus) are complex retroviruses that infect a broad range of mammals, including humans. Unlike many other retrovirus genera, lentiviruses have only rarely been incorporated into the mammalian germline.
Roziah Kambol +5 more
core +4 more sources
Titration of Lentivirus Vectors
Cold Spring Harbor Protocols, 2018 The titer of a lentivirus vector is often expressed in transducing units per milliliter. This is a functional titer that reflects the lentivirus’ ability to transduce a particular cell line under specific conditions.
Miguel Sena-Esteves, Guangping Gao
core +3 more sources
Human Retrovirus Genomic RNA Packaging
Viruses, 2022 Two non-covalently linked copies of the retrovirus genome are specifically recruited to the site of virus particle assembly and packaged into released particles.
Heather M. Hanson +3 more
doaj +1 more source
The Battle between Retroviruses and APOBEC3 Genes: Its Past and Present
Viruses, 2021 The APOBEC3 family of proteins in mammals consists of cellular cytosine deaminases and well-known restriction factors against retroviruses, including lentiviruses.
Keiya Uriu +3 more
doaj +1 more source
Journal of Visualized Experiments, 2009 RNA interference (RNAi) is a system of gene silencing in living cells. In RNAi, genes homologous in sequence to short interfering RNAs (siRNA) are silenced at the post-transcriptional state. Short hairpin RNAs, precursors to siRNA, can be expressed using lentivirus, allowing for RNAi in a variety of cell types.
Xiaoyin, Wang, Michael, McManus
openaire +2 more sources
Identification of a small molecule for enhancing lentiviral transduction of TÂ cells
Molecular Therapy: Methods & Clinical Development, 2023 Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies.
Paulina Malach +10 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 Surfactant protein B (SPB) deficiency is a severe monogenic interstitial lung disorder that leads to loss of life in infants as a result of alveolar collapse and respiratory distress syndrome.
Altar M. Munis +2 more
doaj +1 more source
Advances in Lentivirus Purification
Biotechnology Journal, 2020 AbstractLentiviral vectors (LVs) have been increasingly used as a tool for gene and cell therapies since they can stably integrate the genome in dividing and nondividing cells. LV production and purification processes have evolved substantially over the last decades.
Ana Sofia, Moreira +5 more
openaire +2 more sources
Lentivirus-mediated Prl8a2 overexpression.
, 2021 (A) GFP signals in 293T cells transfected with Prl8a2 overexpression vectors. (B) Western blot analysis revealed Prl8a2 expression in 293T cells after transfection. NS, non-specific band. (TIF)
Lili Du (500104) +11 more
core +1 more source
SARS-CoV-2 Neutralization Assay System using Pseudo-lentivirus [PDF]
, 2023 BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects humans' lower respiratory tracts and causes coronavirus disease-2019 (COVID-19).
Ono, Chikako +9 more
core +3 more sources