Results 11 to 20 of about 166,720 (266)

An endogenous lentivirus in the germline of a rodent [PDF]

open access: yes, 2022
Lentiviruses (genus Lentivirus) are complex retroviruses that infect a broad range of mammals, including humans. Unlike many other retrovirus genera, lentiviruses have only rarely been incorporated into the mammalian germline.
Roziah Kambol   +5 more
core   +1 more source

Lentivirus-mediated Prl8a2 overexpression.

open access: yes, 2021
(A) GFP signals in 293T cells transfected with Prl8a2 overexpression vectors. (B) Western blot analysis revealed Prl8a2 expression in 293T cells after transfection. NS, non-specific band. (TIF)
Lili Du (500104)   +11 more
core   +1 more source

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

open access: yes, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Candrian, Christian   +9 more
core   +1 more source

Lentivirus-mediated knockdown of P27RF-Rho inhibits hepatocellular carcinoma cell growth [PDF]

open access: yes, 2017
Aim of the study: To investigate the effects of P27RF-Rho on hepatocellular carcinoma (HCC) cell growth and explore the possibility of using it as a novel therapeutic target for liver cancer treatment.
Guofu Chen   +4 more
core   +1 more source

Lentivirus-mediated circMEF2A1 function investigation in vivo.

open access: yes, 2023
(A, B) qRT-PCR analysis of circMEF2A1 in the cDNA samples generated from the breast muscles of LV-si-circMEF2A1, LV-si-NC, LV-ov-circMEF2A1, and LV-ov-NC infected chicks, n = 3.
Yuqi Chen (602230)   +10 more
core   +1 more source

Inositol Phosphates and Retroviral Assembly: A Cellular Perspective

open access: yesViruses, 2021
Understanding the molecular mechanisms of retroviral assembly has been a decades-long endeavor. With the recent discovery of inositol hexakisphosphate (IP6) acting as an assembly co-factor for human immunodeficiency virus (HIV), great strides have been ...
Clifton L. Ricaña, Robert A. Dick
doaj   +1 more source

INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes

open access: yesMolecular Therapy: Methods & Clinical Development, 2017
Integration of new DNA into cellular genomes mediates replication of retroviruses and transposons; integration reactions have also been adapted for use in human gene therapy.
Eric Sherman   +17 more
doaj   +1 more source

Lentivirus-mediated circMEF2A2 function investigation in vivo.

open access: yes, 2023
(A, B) qRT-PCR analysis of circMEF2A2 in the cDNA samples generated from the breast muscles of LV-si-circMEF2A2, LV-si-NC, LV-ov-circMEF2A2, and LV-ov-NC infected chicks, n = 3.
Yuqi Chen (602230)   +10 more
core   +1 more source

HIV Diagnosis and Treatment through Advanced Technologies

open access: yesFrontiers in Public Health, 2017
Human immunodeficiency virus (HIV) is the chief contributor to global burden of disease. In 2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages and leading cause for people aged 30–44 years. It is classified as a
Hafiza Fizzah Zulfiqar   +10 more
doaj   +1 more source

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

open access: yeseLife, 2019
Direct conversion of human somatic fibroblasts into induced neurons (iNs) allows for the generation of functional neurons while bypassing any stem cell intermediary stages.
Joseph Herdy   +9 more
doaj   +1 more source

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