Results 101 to 110 of about 166,720 (266)
, 2016 Measurement of cell apoptosis by FACS at 48 h post transfection with the shLuman lentivirus and the shRNA-negative lentivirus (mean ± SEM, n = 3).
Nan Wang (21935) +6 more
core +1 more source
Lentivirus hos små idisslare [PDF]
, 2021 Lentivirus är ett genus bestående av icke-onkogena virus i virusfamiljen Retroviridae, subfamilj Orthoretrovirinae, som karaktäriseras av lång inkubationstid, snabb mutationstakt och en omfattande motståndskraft mot värdens immunförsvar.
Hedlund Salenstedt, Emelie
core
m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
Advanced Science, EarlyView.This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang +26 more
wiley +1 more source
Advanced Science, EarlyView.An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu +11 more
wiley +1 more source
Localizzazione sinoviale di lentivirus ovino.
, 1990 Un lentivirus ovino è stato isolato tramite espianto di membrana sinoviale carpale di una pecora sieropositiva asintomatica in un gregge a bassa prevalenza di infezione da lentivirus.
E. Taccini +5 more
core
Advanced Science, EarlyView.sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang +7 more
wiley +1 more source
Monitoring Lentivirus Vector Stocks for Replication-Competent Viruses
, 2018 The potential emergence of replication-competent lentiviruses (RCLs) during vector production and the significant biosafety risk that this represents has led to the development of lentivirus vector production systems to minimize the risk of generating ...
Miguel Sena-Esteves, Guangping Gao
core +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science, EarlyView.ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Production of High-Titer Retrovirus and Lentivirus Vectors
, 2018 The most commonly used method for production of retrovirus and lentivirus vectors in research laboratories is of transient transfection of 293T cells with a lentivirus vector plasmid, packaging genome plasmid(s), and an envelope expression plasmid.
Miguel Sena-Esteves, Guangping Gao
core +1 more source
Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis
Advanced Science, EarlyView.This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun +15 more
wiley +1 more source