Results 11 to 20 of about 122,780 (298)
SARS-CoV-2 Neutralization Assay System using Pseudo-lentivirus
Indonesian Biomedical Journal, 2023 BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects humans' lower respiratory tracts and causes coronavirus disease-2019 (COVID-19).
Anastasia Armimi +9 more
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Advances in Lentivirus Purification [PDF]
Biotechnology Journal, 2020 AbstractLentiviral vectors (LVs) have been increasingly used as a tool for gene and cell therapies since they can stably integrate the genome in dividing and nondividing cells. LV production and purification processes have evolved substantially over the last decades.
Manuel J.T. Carrondo +5 more
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Turkish Journal of Hematology, 2023 Objective: Hemophilia A is an X-linked recessive bleeding disorder caused by a deficiency of plasma coagulation factor VIII (FVIII), and it accounts for about 80%-85% of all cases of hemophilia.
Cansu Hemşinlioğlu +14 more
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Journal of Visualized Experiments, 2009 RNA interference (RNAi) is a system of gene silencing in living cells. In RNAi, genes homologous in sequence to short interfering RNAs (siRNA) are silenced at the post-transcriptional state. Short hairpin RNAs, precursors to siRNA, can be expressed using lentivirus, allowing for RNAi in a variety of cell types.
Xiaoyin, Wang, Michael, McManus
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Restriction of lentivirus in monkeys [PDF]
Proceedings of the National Academy of Sciences, 2002 Retroviruses are able to cross species barriers and have done so many times throughout evolution. Perhaps as a consequence, dominant mechanisms have arisen to block infection by murine retroviruses in mice (restriction factor Fv1) and humans (restriction factor Ref1), as well as in other mammals.
Greg J. Towers +2 more
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An endogenous lentivirus in the germline of a rodent
Retrovirology, 2022 AbstractLentiviruses (genus Lentivirus) are complex retroviruses that infect a broad range of mammals, including humans. Unlike many other retrovirus genera, lentiviruses have only rarely been incorporated into the mammalian germline. However, a small number of endogenous retrovirus (ERV) lineages have been identified, and these rare genomic “fossils ...
Roziah Kambol +2 more
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Fibrin-mediated lentivirus gene transfer: Implications for lentivirus microarrays [PDF]
Journal of Controlled Release, 2010 We employed fibrin hydrogel as a bioactive matrix for lentivirus mediated gene transfer. Fibrin-mediated gene transfer was highly efficient and exhibited strong dependence on fibrinogen concentration. Efficient gene transfer was achieved with fibrinogen concentration between 3.75 and 7.5mg/ml.
Stelios T. Andreadis +3 more
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Intramuscular Delivery of Gene Therapy for Targeting the Nervous System
Frontiers in Molecular Neuroscience, 2020 Virus-mediated gene therapy has the potential to deliver exogenous genetic material into specific cell types to promote survival and counteract disease.
Andrew P. Tosolini +2 more
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Retrogradely Transportable Lentivirus Tracers for Mapping Spinal Cord Locomotor Circuits
Frontiers in Neural Circuits, 2018 Retrograde tracing is a key facet of neuroanatomical studies involving long distance projection neurons. Previous groups have utilized a variety of tools ranging from classical chemical tracers to newer methods employing viruses for gene delivery.
Imran S. Sheikh +7 more
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Molecular Studies of HTLV-1 Replication: An Update
Viruses, 2016 Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered. Studies on HTLV-1 have been instrumental for our understanding of the molecular pathology of virus-induced cancers.
Jessica L. Martin +4 more
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