Results 21 to 30 of about 122,780 (298)
Foamy Virus Vectors for HIV Gene Therapy
Viruses, 2013 Highly active antiretroviral therapy (HAART) has vastly improved outcomes for patients infected with HIV, yet it is a lifelong regimen that is expensive and has significant side effects.
Grant D. Trobridge, Miles E. Olszko
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Veterinární Medicína, 2001 In this study, recombinant histidine tagged p25 capsid protein of Maedi-Visna virus was developed. Part of the viral genome coding p25 protein was positioned downstream and in frame with a metal binding domain in pRSET-B vector.
D. Molinková
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mBio, 2020 Despite their exceptional potencies, the broad tropism of most commonly used lentivirus (LV) vectors limits their use for targeted gene delivery in vivo.
Christina L. Parker +4 more
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Upregulation of ASPP2 expression alleviates the development of proliferative vitreoretinopathy in a rat model [PDF]
International Journal of Ophthalmology, 2021 AIM: To investigate whether upregulation of apoptosis-stimulating p53 protein 2 (ASPP2) expression could alleviate the development of proliferative vitreoretinopathy (PVR) in a rat model. METHODS: ASPP2-lentivirus or scrambled-lentivirus were transfected
Yan-Kun Yue +3 more
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Beyond retrovirus infection: HIV meets gene therapy
Genetics and Molecular Biology, 2006 The human immunodeficiency virus (HIV) is classified as a retrovirus because of its RNA genome and the fact that it requires reverse transcriptase to convert it into DNA.
Flávia Helena da Silva +2 more
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CLEAR Strategy Inhibited HSV Proliferation Using Viral Vectors Delivered CRISPR-Cas9
Pathogens, 2023 Herpes simplex virus type 1 (HSV-1) is a leading cause of encephalitis and infectious blindness. The commonly used clinical therapeutic drugs are nucleoside analogues such as acyclovir.
Min Ying +9 more
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Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005 Estudou-se a capacidade do vírus da artrite-encefalite dos caprinos (CAEV) infectar o feto ou o cabrito neonato pela via de transmissão transplacentária ou no momento do parto.
M.C.C.S.H. Lara +2 more
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Viruses, 2023 Feline immunodeficiency virus (FIV) is a lentivirus in the family Retroviridae that infects domestic cats resulting in an immunodeficiency disease featuring a progressive and profound decline in multiple sets of peripheral lymphocytes. Despite compelling
Brian G. Murphy +6 more
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FIV: from lentivirus to lentivector [PDF]
The Journal of Gene Medicine, 2004 Molecular virological understanding of the feline immunodeficiency virus (FIV) life cycle is increasing, facilitating rational derivation of improved vectors from this non-primate lentivirus. The packaging signal has been mapped, a central DNA flap has been identified, and class I integrase mutants have been validated.
Eric M. Poeschla, Dyana T. Saenz
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The Inside Out of Lentiviral Vectors
Viruses, 2011 Lentiviruses induce a wide variety of pathologies in different animal species. A common feature of the replicative cycle of these viruses is their ability to target non-dividing cells, a property that constitutes an extremely attractive asset in gene ...
Stéphanie Durand, Andrea Cimarelli
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