Results 281 to 290 of about 319,296 (404)

Effects of Combination Treatment with Leptin and Liraglutide on Glucose Metabolism in Insulin-Dependent Diabetic Mice. [PDF]

open access: yesInt J Mol Sci
Fu L   +9 more
europepmc   +1 more source

Enhanced mitochondrial respiration in peripheral blood mononuclear cells (PBMCs) from young children with overweight/obesity and insulin resistance

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
We investigated measures of mitochondrial function in certain types of blood cells and metabolism in 65 children, 5–10 years old. Compared to children of normal weight (n = 20), children with overweight/obesity (n = 28) and especially those with insulin resistance (n = 17), differed in how their cells produced energy.
Eugenia Carvalho   +5 more
wiley   +1 more source

Changes After Leptin Administration in Partial Lipodystrophy and Factors Associated With Hepatic and Metabolic Response. [PDF]

open access: yesJ Endocr Soc
Akinci B   +7 more
europepmc   +1 more source

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano   +3 more
wiley   +1 more source

Protective immune response against Rhodococcus equi: An innate immunity‐focused review

open access: yesEquine Veterinary Journal, Volume 57, Issue 3, Page 563-586, May 2025.
Abstract Rhodococcus equi causes pyogranulomatous pneumonia in foals and immunocompromised people. Despite decades of research efforts, no vaccine is available against this common cause of disease and death in foals. The purpose of this narrative review is to summarise the current understanding of interactions between R. equi and the host innate immune
Bibiana Petri da Silveira   +4 more
wiley   +1 more source

Is Leptin Concentration Associated with the Insulin Resistance Syndrome in Nondiabetic Men?

open access: bronze, 1999
Steven M. Haffner   +4 more
openalex   +1 more source

Serum Leptin Concentrations and Body Fat in Healthy Premature and Term Infants. • 1373 [PDF]

open access: bronze, 1997
Christoph Fusch   +3 more
openalex   +1 more source

Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake

open access: yesThe FEBS Journal, EarlyView.
Estrogen is regulated by the rate‐limiting enzyme aromatase. This study examines how neuroestrogens, estrogen produced in the brain, regulate appetite through the hypothalamus. Using ovariectomized, aromatase knockout, and brain‐specific aromatase‐restored mice, the study found that neuroestrogens suppress appetite by influencing genes like Mc4r.
Takanori Hayashi   +8 more
wiley   +1 more source

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