Results 81 to 90 of about 165,445 (252)

Possible pharmacological role of Leptin medication in pregnancy

, 2021
Through this Thesis I tried to explore the multiple options of using Leptin as a medical tool, I chose to focus on the role of Leptin as a key factor, whose deficiency may impair pregnancy processes, and chose to do my best in arising the awareness of ...
Botchan, Shay Nohar
core  

Cortical Thickness and Appetite Hormones in Adolescent Obesity and Binge Eating Disorder: A Comparative Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined cortical thickness and appetite‐regulating hormones—neuropeptide Y (NPY) and ghrelin—to better understand the neurobiological mechanisms underlying binge eating disorder (BED) and obesity in adolescence. We compared adolescents with BED and obesity, adolescents with obesity without BED, and healthy controls (HCs),
Serkan Turan, İbrahim Mert Erbaş, Fatma Ceren Sarıoğlu, Berrin Çavuşoğlu, Ezgi Molla, Ali Rıza Şişman, Sevay Alsen Güney, Handan Güleryüz, Ayhan Abacı, Yeşim Öztürk, Aynur Pekcanlar Akay   +10 more
wiley   +1 more source

Insulin elevates leptin secretion and mRNA levels via cyclic AMP in 3T3-L1 adipocytes deprived of glucose

Heliyon, 2016
Aims: Leptin plays an important role in the pathogenesis of obesity and diabetes, yet the regulatory mechanisms of this hormone have not been fully elucidated.
Tomomi Tsubai, Yukihiro Noda, Kazuma Ito, Makoto Nakao, Yusuke Seino, Yutaka Oiso, Yoji Hamada   +6 more
doaj   +1 more source

GLP‐1 Receptor Agonism Exacerbates Activity‐Based Anorexia in Mice

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Glucagon‐like peptide‐1 receptor (GLP‐1R) agonists reduce food intake and body weight, suggesting they should be avoided in anorexia nervosa. However, preclinical evidence that these drugs reduce activity and reward‐seeking behavior raises the possibility that they might attenuate the compulsive‐like hyperactivity central to ABA ...
Amit Thakar, Travis E. Brown, Shane T. Hentges   +2 more
wiley   +1 more source

Leptin and peroxisome proliferator activated receptor alpha: understanding their contribution towards normalising the programmed phenotype in the peripheral tissues of IUGR offspring

, 2010
In a rat model of intrauterine growth restriction (IUGR) induced by maternal global undernutrition, adult offspring are obese with associated metabolic disturbances. These metabolic abnormalities are all augmented by feeding a high calorie postnatal diet
Garratt, Emma
core   +1 more source

The leptin system and its expression at different nutritional and pregnant stages in lined seahorse (Hippocampus erectus)

Biology Open, 2016
Leptin is an essential hormone for the regulation of energy metabolism and food intake in vertebrate animals. To better understand the physiological roles of leptin in nutrient regulation in paternal ovoviviparous fish (family Syngnathidae), the present ...
Huixian Zhang, Geng Qin, Yanhong Zhang, Shuisheng Li, Qiang Lin   +4 more
doaj   +1 more source

Leptin-induced endothelium-dependent vasorelaxation of peripheral arteries in lean and obese rats: role of nitric oxide and hydrogen sulfide. [PDF]

, 2014
Adipose tissue hormone leptin induces endothelium-dependent vasorelaxation mediated by nitric oxide (NO) and endothelium-derived hyperpolarizing factors (EDHF).
M Whiteman (13292643), ME Wood (14457903), A Gertler (21840101), A Jamroz-Wiśniewska (21840098), J Bełtowski (21840104), G Solomon (13514521)   +5 more
core   +4 more sources

Beyond BMI: Unsupervised Machine Learning Clustering of Bioelectrical Impedance Phenotypes Is Associated With Weight‐Recovery Trajectories in Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To identify data‐driven body composition phenotypes in patients with moderate‐to‐extreme anorexia nervosa (AN) using machine learning (ML) clustering of bioelectrical impedance analysis (BIA) parameters, and to test whether these phenotypes have specific psychopathological and childhood trauma profiles while correlating with early ...
Emanuele Cassioli, Gaia Maiolini, Eleonora D'Areglia, Livio Tarchi, Eleonora Rossi, Veronica Ceccarelli, Cristiano Dani, Luca Zompa, Chiara Ranieri, Enrico Lodovici, Anita Nannoni, Valdo Ricca, Giovanni Castellini   +12 more
wiley   +1 more source

Leptin serum and disease activity in spondyloarthritis [PDF]

, 2020
Background: Spondyloarthritis (SpA) is an active chronic inflammatory disease involving pro-inflammatory cytokines; one of which is leptin. This study aimed to determine correlation between leptin serum level and disease activity in SpA patients. Method:
Luluch Mulyani, Yuliasih
core   +1 more source

Adaptive Evolution of Leptin in Heterothermic Bats [PDF]

, 2011
PMCID: PMC3217946This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Stephen J Rossiter, Shuyi Zhang, Yuan Lihong, Zuo, X, Zuo Xueguo, Gareth Jones, He, Guimei, Lin Benfu, Rossiter Stephen J., Rossiter, SJ, Zhang, Shuyi, Lin, B, Zhao, X, Zhao Xudong, Geiser Fritz, Geiser, F, Lihong Yuan, Yuan, Lihong, Fritz Geiser, He Guimei, He Lingjiang, Rossiter, Stephen J, Geiser, Fritz, He, Lingjiang, Zhang, S, Lingjiang He, Zuo, Xueguo, Lin, Benfu, Stephen J. Rossiter, Xudong Zhao, He, G, Zhao, Xudong, Yuan, L, Guimei He, Zhang Shuyi, Benfu Lin, Xueguo Zuo, He, L, Jones Gareth, Jones, Gareth, Jones, G   +40 more
core   +2 more sources