Results 81 to 90 of about 186,310 (210)

Leptin and Exercise

Experimental Biology and Medicine, 2002
Short-term exercise (<60 min) studies suggest that leptin concentrations are not acutely affected in healthy males and females. Most reports of reductions in serum leptin may be attributed to circadian rhythms or hemoconcentration. For long-term (≥60 min) exercise, a reduction in leptin concentrations reported from 1 to 3 hr of running or cycling ...
Robert R, Kraemer, Hongnan, Chu, V Daniel, Castracane   +2 more
openaire   +2 more sources

Differential modulation of arcuate nucleus and mesolimbic gene expression levels by central leptin in rats on short-term high-fat high-sugar diet.

PLoS ONE, 2014
ObjectiveLeptin resistance is a common hallmark of obesity. Rats on a free-choice high-fat high-sugar (fcHFHS) diet are resistant to peripherally administered leptin. The aim of this study was to investigate feeding responses to central leptin as well as
José K van den Heuvel, Leslie Eggels, Eric Fliers, Andries Kalsbeek, Roger A H Adan, Susanne E la Fleur   +5 more
doaj   +1 more source

Effects of Leptin on the Skeleton.

Endocrine reviews, 2018
Leptin originates in adipocytes, including those in bone marrow, and circulates in concentrations 20 to 90 times higher than those in the cerebrospinal fluid.
I. Reid, P. Baldock, J. Cornish
semanticscholar   +1 more source

Long-duration leptin transgene expression in dorsal vagal complex does not alter bone parameters in female Sprague Dawley rats

Bone Reports
The hypothalamus and dorsal vagal complex (DVC) are both important for integration of signals that regulate energy balance. Increased leptin transgene expression in either the hypothalamus or DVC of female rats was shown to decrease white adipose tissue ...
Russell T. Turner, Adam J. Branscum, Urszula T. Iwaniec   +2 more
doaj   +1 more source

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice

Reproductive Biology and Endocrinology, 2018
Background Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms.
Xiaotong Wang, Xiaoke Zhang, Lian Hu, Honggang Li   +3 more
doaj   +1 more source

Multiple Requirements for Rab GTPases in the Development of Drosophila Tracheal Dorsal Branches and Terminal Cells

G3: Genes, Genomes, Genetics, 2020
Benedikt T. Best, Maria Leptin
doaj   +1 more source

Leptin action in normal and pathological pregnancies

Journal of Cellular and Molecular Medicine, 2017
Leptin is now considered an important signalling molecule of the reproductive system, as it regulates the production of gonadotrophins, the blastocyst formation and implantation, the normal placentation, as well as the foeto‐placental communication ...
A. Pérez-Pérez, A. Toro, T. Vilariño-García, Julieta L. Maymó, P. Guadix, J. Dueñas, M. Fernández-Sánchez, C. Varone, V. Sánchez-Margalet   +8 more
semanticscholar   +1 more source

The Effects of Leptin Replacement on Neural Plasticity

Neural Plasticity, 2016
Leptin, an adipokine synthesized and secreted mainly by the adipose tissue, has multiple effects on the regulation of food intake, energy expenditure, and metabolism.
Gilberto J. Paz-Filho
doaj   +1 more source

LEPTIN AND OBESITY – NEUROENDOCRINE , METABOLIC AND ATHEROGENIC EFFECTS OF LEPTIN

Zdravniški Vestnik, 2003
Background. Leptin is an adipocyte-derived hormone that was recently discovered. Leptin and leptin resistance play an important role in the pathogenesis of obesity.
Mišo Šabovič, Alenka Mavri
doaj  

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Nature, 1997
C. Montague, I. Farooqi, J. Whitehead, M. Soos, H. Rau, N. Wareham, C. Sewter, J. Digby, S. Mohammed, J. Hurst, C. Cheetham, Alison R. Earley#, A. Barnett, J. Prins, S. O’Rahilly   +14 more
semanticscholar   +1 more source