Results 61 to 70 of about 76,631 (314)
Endocrine Journal, 2017 Leptin and visfatin are implicated in breast cancer risk but studies accounting for bioavailability of leptin are sparse. Reports on the association of leptin gene (LEP) and leptin receptor gene (LEPR) polymorphisms with breast cancer are also inconsistent.
Chrishani, Rodrigo +5 more
openaire +3 more sources
Leptin and leptin receptors during malaria infection in mice [PDF]
Folia Parasitologica, 2002 Leptin, which is involved in a range of physiological processes, could be an important factor in the pathogenesis of malaria. We found that levels of leptin in serum and urine in Plasmodium berghei-infected mice increased progressively after infection, reaching a maximum value on day 6 post-infection. Serum values were approximately five-fold higher in
Magdalena, Pulido-Mendez +2 more
openaire +2 more sources
Advanced Science, EarlyView.This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He +7 more
wiley +1 more source
BMC Cancer, 2008 Background Leptin, a 16 kDa polypeptide hormone, implicated in various physiological processes, exerts its action through the leptin receptor, a member of the class I cytokine receptor family. Both leptin and leptin receptor have recently been implicated
Anyanwu Stanley N +9 more
doaj +1 more source
Evidence for positive selection on the leptin gene in Cetacea and Pinnipedia. [PDF]
PLoS ONE, 2011 The leptin gene has received intensive attention and scientific investigation for its importance in energy homeostasis and reproductive regulation in mammals.
Li Yu +8 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu +9 more
wiley +1 more source
Peripheral nerve demyelination and a leptin receptor mutation: The obese Zucker rat sciatic nerve demyelination occurs with a centripetal pattern defect [PDF]
, 2020 Jacques Gilloteaux +3 more
openalex +1 more source
Leptin Signalling in the Ovary of Diet-Induced Obese Mice Regulates Activation of Nod-Like Receptor Protein 3 Inflammasome [PDF]
, 2021 Marek Adamowski +6 more
openalex +1 more source
Advanced Science, EarlyView.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source
Receptor-Mediated Transcytosis of Leptin through Human Intestinal Cells In Vitro
International Journal of Cell Biology, 2010 Gastric Leptin is absorbed by duodenal enterocytes and released on the basolateral side towards the bloodstream. We investigated in vitro some of the mechanisms of this transport.
Philippe G. Cammisotto +5 more
doaj +1 more source