Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software
The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines.
P. V. Shadrin +3 more
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A critically ill patient after a colchicine overdose below the lethal dose: a case report [PDF]
Background Although 0.8 mg/kg is considered a lethal dose of colchicine, fatal cases of patients who followed a critical disease course after an intake below this lethal dose have been reported.
Ichiro Hirayama +4 more
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Artemia salina as an animal model for the preliminary evaluation of snake venom-induced toxicity
Lethality and cytotoxicity assays of snake venoms and their neutralization by antivenom require many mice for the experiments. Recent developments have prompted researchers to seek alternative strategies that minimize the use of mice in line with Russel ...
Mitchel Otieno Okumu +6 more
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LARVICIDAL ACTIVITY OF THE METHANOLIC EXTRACT OF Warbugia ugadensis SEED OIL ON Aedes aegypti
Mosquito is a vector implicated with Vector-borne diseases such as malaria (Anopheles’ species) dengue (Aedes species) and west Nile fever (Culex species).
JudyAnn Matura +2 more
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BioRssay: an R package for analyses of bioassays and probit graphs
Dose–response relationships reflect the effects of a substance on organisms, and are widely used in broad research areas, from medicine and physiology, to vector control and pest management in agronomy. Furthermore, reporting on the response of organisms
Piyal Karunarathne +3 more
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Ex vivo expanded decidua-basalis(DB)-derived mesenchymal stem cells (MSCs) obtained from single donors have demonstrated therapeutic benefits in in vitro and in vivo studies.
Priya Subramani +11 more
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Transfer of Radio-Adaptation via Serum: A Preliminary Report [PDF]
Introduction: Adaptive response is one of the important concepts in radiobiology. The present report aimed to transfer the radio-adaptation via serum.
Ehsan Khodamoradi +6 more
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Effect of ethyl acetate fraction of Costus afer on glycaemic control and essential haematological and biochemical indices of streptozotocin-induced diabetic rats [PDF]
Introduction: Diabetes mellitus is a common global cause of sudden unpredictable death if undiagnosed and untreated. Costus afer (Costaceae) is a tropical plant with quite a lot of pharmacological properties.
Obiajulu Christian Ezeigwe +4 more
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Radiosensitivity of Two Local Chili Varieties to Gamma Rays
Genetic variation is needed for developing new superior varieties in plant breeding. Genetic variation of chili plants could be increased by inducing mutation with gamma rays irradiation.
Makhziah Makhziah +1 more
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Lethal Dose of Calcium Bentonite in Wistar Rats
Background: Calcium bentonite is a type of clay produced by a devitrification of volcanic ash which is often used as a traditional medicine to absorb toxins and waste products of metabolism.
Dwika Audiyananda +2 more
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