Results 51 to 60 of about 345,070 (206)

Non-Lethal Dose-Response Models Replace Lethal Bioassays for Predicting the Hazard of Para-Aminopropiophenone to Australian Wildlife

open access: yesAnimals, 2023
Para-aminopropiophenone (PAPP) is a potent methaemoglobin (MetHb) forming agent used for the lethal control of exotic carnivores and mustelids. To assess the sensitivity of Australian wildlife to PAPP we developed an in vivo assay that did not use death ...
Clive A. Marks   +2 more
doaj   +1 more source

Hurdles in investigating UVB damage in the putative ancient asexual Darwinula stevensoni (Ostracoda, Crustacea) [PDF]

open access: yes, 2013
Ostracoda or mussel-shrimps are small, bivalved Crustacea. Because of their excellent fossil record and their broad variety of reproductive modes, ostracods are of great interest as a model group in ecological and evolutionary research.
Martens, Koenraad   +3 more
core  

Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology [PDF]

open access: yes, 2017
Staphylococcal enterotoxin B (SEB) is a bacterial superantigen that binds the receptors in the APC/T cell synapse and causes increased proliferation of T cells and a cytokine storm syndrome in vivo.
Carter, Alun J   +10 more
core   +2 more sources

Alternative Methods for the Median Lethal Dose (LD50) Test: The Up-and-Down Procedure for Acute Oral Toxicity [PDF]

open access: yesILAR Journal, 2002
The authors have developed an improved version of the up-and-down procedure (UDP) as one of the replacements for the traditional acute oral toxicity test formerly used by the Organisation for Economic Co-operation and Development member nations to characterize industrial chemicals, pesticides, and their mixtures. This method improves the performance of
Amy, Rispin   +8 more
openaire   +2 more sources

The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]

open access: yes, 1990
Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B   +7 more
core   +1 more source

Acute Toxicity (Lethal Dose 50 Calculation) of Herbal Drug Somina in Rats and Mice

open access: yesPharmacology & Pharmacy, 2015
Somina (herbal preparation) prepared by Hamdard Laboratories (Waqf) Pakistan is a mixture of five different medicinal plants, widely prescribed for the treatment of mental illness. For acute toxicity, the Karber arithmetic method for the calculation of LD50 and Hodge and Sterner toxicity scale was used. In this study, different doses (10, 100, 285, 500,
openaire   +2 more sources

Assessment of the Antinociceptive, Anti-Inflammatory, and Acute Toxicity Effects of Solanum Dulcamara Essential Oil in Male Mice

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Pain is a complex set of unpleasant sensory, emotional, and cognitive experiences that are relieved with synthetic and herbal remedies. Of course, medicinal plants are more important than chemical drugs due to fewer side effects.
AR Fallahzadeh, S Mohammadi
doaj  

Punica granatum L. protects mice against hexavalent chromium-induced genotoxicity

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2013
This study investigated the chemoprotective effects of Punica granatum L. (Punicaceae) fruits alcoholic extract (PGE) on mice exposed to hexavalent chromium [Cr(VI)].
Renato Ivan de Ávila   +8 more
doaj   +1 more source

Frequency analysis of cytolytic T lymphocyte precursors (CTL-P) generated in vivo during lethal rabies infection of mice. II. Rabies virus genus specificity of CTL-P [PDF]

open access: yes, 1984
Cytolytic T lymphocyte precursors (CTL-P) were sensitized in vivo by intraplantar infection of C57BL/6 mice with a lethal dose of rabies virus, strain ERA (ERA).
Aden   +22 more
core   +1 more source

Determination of Lethal Dose 50 for Induced Mutagenesis in Soybean [Glycine max (L.) Merril] cv. Gepak Kuning Through Ethyl Methane Sulfonate Mutagen

open access: yesAgricultural Science Digest - A Research Journal, 2023
Background: The improvement of the genetic and agronomic properties of cultivated plants can be carried out by various plant breeding methods, including mutation breeding. Mutations in nature are very few and rare. Ethyl Methane Sulfonate (EMS) is a chemical mutagen that can cause random mutations resulting in changes in genetic material.
Nilahayati .   +5 more
openaire   +1 more source

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