LZTS2 Negatively Regulates Centrosomal CEP135 Levels and Microtubule Nucleation
ABSTRACT The microtubule cytoskeleton is a fundamental functional component of the cell. In vertebrate proliferating cells, centrosomes are the primary microtubule organizing center (MTOC), and their dysregulation has been linked to genomic instability and cancer.
Catarina Peneda+4 more
wiley +1 more source
The use of protein supplements in children with cerebral palsy: A scoping literature review. [PDF]
Verreydt I+4 more
europepmc +1 more source
Purification and Properties of a Leucine-binding Protein from Escherichia coli
W.R. Penrose+3 more
openalex +1 more source
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius+6 more
wiley +1 more source
BCAA metabolism in cancer progression and therapy resistance: The balance between fuel and cell signaling. [PDF]
Zhou Y+5 more
europepmc +1 more source
Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
Continuous flow technology is exploited for the generation of bicyclic pyrazolines via photo‐click reactions. These heterocyclic species contain a valuable 3D scaffold along with a polar succinimide moiety. Subsequent antimicrobial testing reveals that halogenated moieties such as chlorine atoms and trifluoromethoxy groups enhance the potency of these ...
Debora Caviglia+4 more
wiley +1 more source
A novel mouse model to study the effects of new therapies for Diamond-Blackfan anemia. [PDF]
Liu YL, Neoman N, Sakamoto KM.
europepmc +1 more source
Vibrational Partition Functions from Bond Order and Populations Relationships
A new computational model is presented that predicts vibrational partition functions using bond orders and populations relationships (QBOP). This model demonstrates that thermochemical energy contributions can be reasonably approximated based on well‐conditioned orbital populations without the need for a costly Hessian calculation.
Barbaro Zulueta, John A. Keith
wiley +1 more source
Low leucine levels in the blood enhance the pathogenicity of neonatal meningitis-causing Escherichia coli. [PDF]
Sun H+15 more
europepmc +1 more source