Results 11 to 20 of about 14,935 (222)

The polo-like kinase 1 (PLK1) inhibitor NMS-P937 is effective in a new model of disseminated primary CD56+ acute monoblastic leukaemia [PDF]

open access: yes, 2013
CD56 is expressed in 15–20% of acute myeloid leukaemias (AML) and is associated with extramedullary diffusion, multidrug resistance and poor prognosis.
A Blair   +55 more
core   +6 more sources

Pediatric acute lymphoblastic leukemia and leukapheresis: CT evidence of hemorrhagic complication

open access: yesEuropean Journal of Radiology Open, 2020
Leukapheresis has been used widely to quickly reduce white blood cell count (WBC) in patients with hyperleukocytosis. Despite its wide utilization, leukapheresis has risks of complication, which have not been thoroughly reported in pediatric patients. No
Benedicta Mutiara Suwita   +1 more
doaj   +1 more source

Efficacy of therapeutic leukapheresis in acute lymphoblastic leukemia presenting with leukostasis: A report of two cases

open access: yesGlobal Journal of Transfusion Medicine, 2021
Therapeutic leukapheresis is performed in patients having hyperleukocytosis, leading to leukostasis. The aim of this study was to evaluate the efficacy of therapeutic leukapheresis in reducing white cell count in leukemic patients with symptoms of ...
Tapti Mohapatra, Prabodha Kumar Das
doaj   +1 more source

Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment [PDF]

open access: yes, 2020
Dendritic cells play a key role in activation of the immune system as potent antigen-presenting cells. This pivotal position, along with the ability to generate dendritic cells from monocytes and ready uptake of antigen, makes them an intriguing vehicle ...
Cox, Cheryl, Hopewell, Emily L.
core   +1 more source

IMPROVEMENT OF LEUKEMIC RETINOPATHY AFTER LEUKAPHERESIS IN CHRONIC MYELOGENOUS LEUKEMIA WITH LEUKOSTASIS

open access: yesIJRETINA (International Journal of Retina), 2020
Introduction: to report a case of bilateral leukemic retinopathy due to leukostasis that was successfully managed by leukapheresis. Case Presentation: 31-year-old male with mild visual disturbance was referred to ophthalmology department.
Ruchyta Ranti   +7 more
doaj   +1 more source

Characteristics of autologous peripheral blood stem cells collection over a one-year period [PDF]

open access: yesMedicinski Glasnik, 2020
Aim To present characteristics of collecting autologous peripheral blood stem cells over a one-year period with an emphasis on efficiency and safety. Methods A retrograde analysis of 24 leukapheresis in 20 adult patients with malignant haematological ...
Gorana Ahmetović-Karić   +2 more
doaj   +1 more source

Analysis on the composition of leukapheresis product – A comparison between MCS+® + and spectra optia® apheresis equipment

open access: yesJournal of Applied Hematology, 2021
INTRODUCTION: Peripheral blood stem cell has become the preferred source for hematopoietic stem cells in both autologous and allogenic transplants. CD34+ cells represent a small proportion of the leukapheresis product content.
Mohandoss Murugesan   +3 more
doaj   +1 more source

Autologous lymphokine-activated killer cell therapy of lymphoproliferative disorders arising in organ transplant recipients [PDF]

open access: yes, 1997
Cell lymphomas which often contain the Epstein-Barr virus (EBV) make up the preponderance of tumors that collectively have been termed posttransplant lymphoproliferative disorders (PTLD).
Alard   +14 more
core   +2 more sources

Leukapheresis Therapy of Chronic Lymphocytic Leukemia [PDF]

open access: yesBlood, 1972
Abstract The effects of repeated leukapheresis with the IBM Blood Cell Separator were assessed in 13 patients with chronic lymphocytic leukemia (CLL). Five patients had from 14 to 25 leukaphereses at intervals ranging from 7 to 33 days. The median total number of lymphocytes removed was 18.0 x 1011 (range 11.9 x 1011-26.6 x 1011). Two of
J E, Curtis, E M, Hersh, E J, Freireich
openaire   +2 more sources

Ex Vivo Model to Assess the Exposure of Patients to Plasticizers from Medical Devices during Pre-CAR-T Cells’ Apheresis

open access: yesToxics, 2022
Background: The treatment of relapsed or refractory leukemia remains a major problem. Among the new therapeutic approaches, the use of modified T lymphocytes, called chimeric antigen receptor T cells (CAR-T cells), seems promising.
Raphaëlle Lautraite   +6 more
doaj   +1 more source

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