Results 21 to 30 of about 14,935 (222)
Relationship between intact HIV-1 proviruses in circulating CD4+ T cells and rebound viruses emerging during treatment interruption. [PDF]
, 2018 Combination antiretroviral therapy controls but does not cure HIV-1 infection because a small fraction of cells harbor latent viruses that can produce rebound viremia when therapy is interrupted. The circulating latent virus reservoir has been documented
Barton, John +13 more
core +1 more source
Normal chemotactic activity of granulocytes obtained by filtration leucapheresis [PDF]
, 1977 The chemotactic activity of granulocytes obtained by the Terumo Filtration Leucapheresis System (F.L.) was examined by the method of Boyden's chamber. The number of cells migrating through the Millipore filter was expressed as the chemotactic activity ...
Kimura, Ikuro +6 more
core +1 more source
Cells, 2020 Background: T lymphocyte collection through leukapheresis is an essential step for chimeric antigen receptor T (CAR-T) cell therapy. Timing of apheresis is challenging in heavily pretreated patients who suffer from rapid progressive disease and receive T
Felix Korell +11 more
doaj +1 more source
Acute vision loss due to CML leukemic retinopathy reversed with leukapheresis
Clinical Case Reports, 2023 Leukemic retinopathy is a severe complication of severe leukocytosis that results from untreated chronic myelogenous leukemia (CML). Immediate cytoreduction via leukapheresis may reverse ocular manifestations and prevent permanent vision damage.
Sally Leong +3 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2021 Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease.
Julián Sevilla +29 more
doaj +1 more source
Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer. [PDF]
, 2014 BackgroundSipuleucel-T is a US Food and Drug Administration-approved immunotherapy for asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Its mechanism of action is not fully understood.
Amling, Christopher L +12 more
core +2 more sources
Current Problems in Cancer: Case Reports, 2023 Leukapheresis is a resource-intensive and high-risk treatment with unclear benefits when used for leukostasis syndrome in hematologic malignancies.
Bowen He +3 more
doaj +1 more source
Leukapheresis and Granulocyte Transfusion
CRC Critical Reviews in Clinical Laboratory Sciences, 1979 Granulocytes for transfusion can now be obtained from normal donors by one of four techniques that involve either centrifugation or reversible adhesion of granulocytes to nylon fibers. The leukapheresis process appears to be safe for donors and standards for the selection and care of donors are being formulated.
Jeffrey McCullough, Donald J. Higby
openaire +3 more sources
Drugs in Context, 2021 Drug therapy of immune-mediated inflammatory arthropathies is not always satisfactory, and there is a risk of adverse events. Granulocyte and monocyte/macrophage apheresis (GMA) is a non-pharmacological therapeutic option that is beneficial and very well
Ana Victoria Carro Martínez +2 more
doaj +1 more source
Inhibition of MDR1 does not sensitize primitive chronic myeloid leukemia CD34+ cells to imatinib [PDF]
, 2009 <p><b>Objective:</b> To investigate the interaction of imatinib mesylate (IM) with the clinically relevant adenosine triphosphate-binding cassette efflux transporter MDR1 (ABCB1) in cells from patients with chronic myeloid leukemia (CML)
Hatziieremia, S. +4 more
core +1 more source