Results 31 to 40 of about 14,935 (222)

Gene induction during differentiation of human monocytes into dendritic cells: an integrated study at the RNA and protein levels [PDF]

, 2001
Changes in gene expression occurring during differentiation of human monocytes into dendritic cells were studied at the RNA and protein levels. These studies showed the induction of several gene classes corresponding to various biological functions ...
Angénieux, C., Bausinger, H., Cazenave, J. P., de la Salle, H., Fricker, D., Hanau, D., Luche, S., Rabilloud, T., Strub, J. M., Van Dorsselaer, A.   +9 more
core   +3 more sources

Rapid Treatment of Leukostasis in Leukemic Mantle Cell Lymphoma Using Therapeutic Leukapheresis: A Case Report

The Scientific World Journal, 2011
We describe a case of severe leukocytosis caused by leukemic mantle cell lymphoma (MCL), complicated by leukostasis with myocardial infarction in which leukapheresis was used in the initial management.
Xuan Duc Nguyen, Paul La Rosée, Thomas Nebe, Harald Klüter, Dieter Buchheidt   +4 more
doaj   +1 more source

T-cell counts in peripheral blood at leukapheresis predict responses to subsequent CAR-T cell therapy

Scientific Reports, 2022
Prediction of responses to chimeric antigen receptor (CAR)-T cell therapies is essential to maximize their therapeutic efficacy for diffuse large B-cell lymphoma (DLBCL).
Fumiya Wada, Tomoyasu Jo, Yasuyuki Arai, Toshio Kitawaki, Chisaki Mizumoto, Junya Kanda, Momoko Nishikori, Kouhei Yamashita, Miki Nagao, Akifumi Takaori-Kondo   +9 more
doaj   +1 more source

Promises and challenges of a decentralized CAR T-cell manufacturing model

Frontiers in Transplantation, 2023
Autologous chimeric antigen receptor-modified T-cell (CAR T) products have demonstrated un-precedent efficacy in treating many relapsed/refractory B-cell and plasma cell malignancies, leading to multiple commercial products now in routine clinical use ...
Manan Shah, Ashley Krull, Lynn Odonnell, Marcos J. de Lima, Evandro Bezerra   +4 more
doaj   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
A. Vabret, Abt, Arbour, Arbour, B. Nal, Bonavia, Caignard, Caignard, Callendret, Callow, Caux, Chapuis, Collins, de Swart, de Witte, Desforges, Desforges, Engelmayer, Esposito, F. Tangy, Ferlazzo, Gagneur, Geijtenbeek, Glew, H. Law, Hahm, Hamdorf, Herbst, Hoarau, J. Millet, Kramer, Kärber, Law, Legge, M. L. Albert, M. Mesel-Lemoine, MacDonald, Mahanty, Movassagh, Muller, N. Escriou, Nogueira, O'Doherty, Olweus, P.-O. Vidalain, Pacanowski, Piqueras, Rosenzwajg, Sallusto, Servet-Delprat, Servet-Delprat, Servet-Delprat, Sizun, Spearman, Spiegel, Thitithanyanont, Thornberry, V. Lorin, Vabret, Wang, Yang, Yeager   +61 more
core   +3 more sources

Therapeutic leukapheresis in a tertiary care hospital: A case series

Asian Journal of Transfusion Science, 2017
Patients presenting with hyperleukocytosis secondary to acute leukemia, with total leukocyte count or blast count more than 100,000/μL are often considered for leukapheresis, especially if clinical signs of leukostasis are present.
Raj Nath Makroo, Brinda Kakkar, Mohit Chowdhry, Soma Agrawal, Shishir Seth, Uday K Thakur   +5 more
doaj   +1 more source

Repeated small-volume exchange transfusion for hyperleukocytosis in pediatric acute leukemia: A retrospective analysis

Frontiers in Pediatrics, 2023
IntroductionLeukapheresis reduces hyperleukocytosis in children with acute leukemia. Although the usefulness of this procedure is under debate, a repeated small-volume exchange transfusion along with leukapheresis yielded satisfactory results ...
Dongxiu Zhang, Hailong Lin, Leting Huang
doaj   +1 more source

A high-throughput microfluidic device based on controlled incremental filtration to enable centrifugation-free, low extracorporeal volume leukapheresis

Scientific Reports, 2022
Leukapheresis, the extracorporeal separation of white blood cells (WBCs) from red blood cells (RBCs) and platelets (PLTs), is a life-saving procedure used for treating patients with cancer and other conditions, and as the initial step in the ...
Dalia L. Lezzar, Fong W. Lam, Ravin Huerta, Anton Mukhamedshin, Madeleine Lu, Sergey S. Shevkoplyas   +5 more
doaj   +1 more source

Leukapheresis in Pediatric Acute Leukemia with Hyperleukocytosis: A Single-Center Experience

Children, 2022
Hyperleukocytosis in pediatric acute leukemia is associated with increased morbidity and mortality and at present there is no consensus on the use of leukapheresis (LPH) for its management.
Sandra Renee Jones, April Rahrig, Amanda J. Saraf   +2 more
doaj   +1 more source

Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy – a case report [PDF]

, 2009
Background: Membrane-bound heat shock protein 70 (Hsp70) serves as a tumor-specific recognition structure for Hsp70-peptide (TKD) plus IL-2 activated NK cells.
Valeria Milani, Stefan Stangl, Rolf Issels, Mathias Gehrmann, Beate Wagner, Kathrin Hube, Doris Mayr, Wolfgang Hiddemann, Michael Molls, Gabriele Multhoff   +9 more
core   +2 more sources