Results 71 to 80 of about 14,935 (222)

Local but no systemic immunomodulation by intraperitoneal treatment of advanced ovarian cancer with autologous T lymphocytes re-targeted by a bi-specific monoclonal antibody [PDF]

, 1997
We have reported a 27% overall anti-tumor response using i.p. immunotherapy of advanced ovarian carcinoma with autologous, ex vivo expanded, T lymphocytes re-targeted with bi-specific monoclonal antibody OC/TR, combined with soluble OC/TR and low-dose ...
Bolhuis, R.L.H. (Reinder), Gratama, J.W. (Jan-Willem), Lamers, C.H.J. (Cor), Stoter, G. (Gerrit), Warnaar, S.O. (Sven)   +4 more
core   +2 more sources

Long Overall Survival After Dendritic Cell Vaccination in Metastatic Uveal Melanoma Patients [PDF]

, 2014
Purpose: To assess the safety and efficacy of dendritic cell vaccination in metastatic uveal melanoma. Design: Interventional case series. Methods: We analyzed 14 patients with metastatic uveal melanoma treated with dendritic cell vaccination.
Aarntzen, E.H.J.G. (Erik), Bol, K.F. (Kalijn), Coulie, P.G. (Pierre), Figdor, C.G. (Carl), Keunen, J.E.E. (Jan), Klein, J.E.M.M. (Annelies) de, Mensink, H.W. (Hanneke), Paridaens, A.D.A. (Dion), Punt, C.J.A. (Cornelis), Schreibelt, G. (Gerty), Vries, I.J.M. (Jolanda) de   +10 more
core   +1 more source

Granulocyte concentrates: Prolonged functional capacity during storage in the presence of phenotypic changes [PDF]

, 2008
Background Granulocyte transfusion has been proposed as a bridging therapy for patients with prolonged ...
Ball, L.M. (Lynne), Boelens, J.J. (Jaap), Bruin, M.C. (Marrie), Drewniak, A. (Agata), Heuvel-Eibrink, M.M. (Marry) van den, Kuijpers, T.W. (Taco W.), Marianne, D.v.d.W. (Wetering), Roos, D. (Dirk), Tool, A.T.J. (Anton), Vrielink, H. (Hans)   +9 more
core   +3 more sources

Impaired hematopoiesis affects apheresis and CAR T‐cell product composition and treatment response

Transfusion, EarlyView.
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy has transformed the treatment of hematologic malignancies, but its success depends on obtaining sufficient CD3+ T‐cell yields during leukapheresis. This can be difficult in heavily pretreated patients, who often show leukopenia and reduced T‐cell fitness.
Hanna Kuhn, Felix Korell, Angela Hückelhoven‐Krauss, Brigitte Neuber, Miriam Stenzinger, Anita Ludwig‐Husemann, Maria‐Luisa Schubert, Patrick Derigs, Kiavasch Farid, Tim Sauer, Sandra Sauer, Carsten Müller‐Tidow, Peter Dreger, Michael Schmitt, Anita Schmitt   +14 more
wiley   +1 more source

Cross-reactivity between HLA-A2-restricted FLU-M1:58–66 and HIV p17 GAG:77–85 epitopes in HIV-infected and uninfected individuals [PDF]

, 2003
Background The matrix protein of the influenza A virus and the matrix and capsid proteins of the human immunodeficiency virus (HIV) share striking structural similarities which may have evolutionary and biological significance.
Paula M Acierno, Danforth A Newton, Edwin A Brown, Lou Maes, John E Baatz, Sebastiano Gattoni-Celli   +5 more
core   +2 more sources

Intra‐apheresis CD34+ cell count: A dynamic approach to predicting peripheral blood stem cell collection yield

Transfusion, EarlyView.
Abstract Background Accurate prediction of peripheral blood stem cell (PBSC) yield is essential for optimizing hematopoietic stem cell collections. Traditional CD34+ prediction formulas often overlook the ongoing recruitment of CD34+ cells during the collection procedure.
Abdullah Alswied, Linda Song, Mame Thioye‐Sall, Leonard N. Chen, Kamille West‐Mitchell, Nan Zhang, Ping Jin, David Stroncek, Anh Dinh   +8 more
wiley   +1 more source

Autologous cancer cell vaccination, adoptive T‐cell transfer, and interleukin‐2 administration results in long‐term survival for companion dogs with osteosarcoma

Journal of Veterinary Internal Medicine, 2020
Background Osteosarcoma (OSA) in dogs is an aggressive bone tumor with frequent chemotherapy failure and translational relevance for human health. Hypothesis/Objectives We hypothesized that dogs with OSA could be treated safely by ex vivo activated T ...
Brian K. Flesner, Gary W. Wood, Pamela Gayheart‐Walsten, F. Lynn Sonderegger, Carolyn J. Henry, Deborah J. Tate, Sandra M. Bechtel, Lindsay L. Donnelly, Gayle C. Johnson, Dae Young Kim, Tammie A. Wahaus, Jeffrey N. Bryan, Noe Reyes   +12 more
doaj   +1 more source

Reprogramming human T cell function and specificity with non-viral genome targeting. [PDF]

, 2018
Decades of work have aimed to genetically reprogram T cells for therapeutic purposes1,2 using recombinant viral vectors, which do not target transgenes to specific genomic sites3,4.
Alkorta-Aranburu, Gorka, Ashworth, Alan, Bacchetta, Rosa, Carmody, David, Carnevale, Julia, Chen, Jeff W, Cho, Min, Del Gaudio, Daniela, Esensten, Jonathan H, Ferris, Andrea L, Greeley, Siri Atma W, Gurumurthy, Channabasavaiah B, Haugwitz, Michael, Herold, Kevan C, Hiatt, Joseph, Hughes, Stephen H, Krystofinski, Paige, Kupfer, Gary M, Lee, Michael R, Leonetti, Manuel D, Li, Han, Li, P Jonathan, Mao, Ying, Marson, Alexander, Matsumoto, Hiroyuki, May, Andrew P, Meffre, Eric, Morell, Montse, Nguyen, David N, Pellerin, Laurence, Puig-Saus, Cristina, Putnam, Amy L, Quadros, Rolen M, Ribas, Antoni, Romberg, Neil, Roncarolo, Maria Grazia, Roth, Theodore L, Saco, Justin, Schickel, Jean-Nicolas, Schumann, Kathrin, Shifrut, Eric, Smith, Baz, Tobin, Victoria, Weissman, Jonathan S, Yu, Ruby   +44 more
core  

Monitoring of haematopoietic stem cell mobilization by targeted DNA methylation analysis for the British Journal of Haematology

British Journal of Haematology, EarlyView.
Wouter H. G. Hubens, Anke Diehlmann, Patrick Wuchter, Wolfgang Wagner   +3 more
wiley   +1 more source

Chimeric Antigen Receptor T‐Cells in Myasthenia Gravis: Advances, Safety Challenges, and Future Directions

Muscle &Nerve, Volume 73, Issue 6, Page 942-951, June 2026.
ABSTRACT This review examines the emerging application of chimeric antigen receptor (CAR) T‐cell therapy in myasthenia gravis (MG), with emphasis on safety, efficacy signals, and future therapeutic potential in treatment‐refractory disease. A comprehensive literature search was conducted across PubMed, medRxiv, bioRxiv, and Google Scholar for studies ...
Tobias Hegelmaier, Alexander Duscha, Christiane Desel, Sarah Stassen, Tim Krzemien, Ann‐Katrin Hennemann, Vaia Pappa, Aiden Haghikia   +7 more
wiley   +1 more source