Results 31 to 40 of about 213,141 (301)
Interaction of cytokine LIF with the lipidic matrix of membranes [PDF]
Компьютерные исследования и моделирование, 2010 Integration of LIF protein into the bilayer lipid membrane causes the formation of ion channels. The data on activity of ion channels formed by recombinant protein from mouse and human origin are shown.
Marina Petrovna Borisova +2 more
doaj +1 more source
Possible Role of Leukemia Inhibitory Factor and Inflammatory Cytokines in The Recurrent Spontaneous Abortion: A Case-Control Study [PDF]
International Journal of Fertility and Sterility, 2023 Background: Despite of long-lasting efforts, in more than 50% of cases, the etiology of recurrent spontaneous abortion (RSA) remains unknown. Leukemia inhibitory factor (LIF) has an essential role in the reproductive process, such as modulating ...
Seyed Mohsen Miresmaeili +4 more
doaj +1 more source
Anti-CD20 Therapy Acts via FcγRIIIA to Diminish Responsiveness of Human Natural Killer Cells [PDF]
, 2015 Natural killer (NK) immune cells mediate antibody-dependent cellular cytotoxicity (ADCC) by aggregating FcγRIIIA/CD16, contributing significantly to the therapeutic effect of CD20 monoclonal antibodies (mAb).
Capuano, Cristina +8 more
core +1 more source
The Regulation of Leukemia Inhibitory Factor [PDF]
Cancer Cell & Microenvironment, 2015 Leukemia inhibitory factor (LIF), a secreted cytokine, plays an important role in a wide array of biological processes including inducing differentiation of leukemia cell, inflammatory response, neuronal development, embryonic implantation, stem cell self-renewal and cancer progression, etc.
Xuetian, Yue, Lihua, Wu, Wenwei, Hu
openaire +2 more sources
BMC Women's Health, 2012 Background Uterine receptivity and implantation are complex processes requiring coordinated expression of molecules by zygote and uterus. Our objective was to evaluate the role of the endometrial expression of leukemia inhibitory factor (LIF) and its ...
Tawfeek Manal A +4 more
doaj +1 more source
Cancer Cell International, 2021 Background Cancer cachexia is a wasting disorder characterized by significant weight loss, and is attributed to skeletal muscle weakness. In the process of cancer development, microRNAs act as oncogenes or tumor suppressors. Moreover, they are implicated
Kairu Xie +12 more
doaj +1 more source
Comparative study of gp130 cytokine effects on corticotroph AtT-20 cells - Redundancy or specificity of neuroimmunoendocrine modulators? [PDF]
, 2004 Objective: This comparative in vitro study examined the effects of all known gp130 cytokines on murine corticotroph AtT-20 cell function. Methods: Cytokines were tested at equimolar concentrations from 0.078 to 10 nM.
Auernhammer, Christoph J. +9 more
core +1 more source
Muscle atrophy reversed by growth factor activation of satellite cells in a mouse muscle atrophy model. [PDF]
PLoS ONE, 2014 Muscular dystrophies comprise a large group of inherited disorders that lead to progressive muscle wasting. We wanted to investigate if targeting satellite cells can enhance muscle regeneration and thus increase muscle mass.
Simon Hauerslev +2 more
doaj +1 more source
Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]
, 2012 This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Beyer, Jörg +11 more
core +1 more source
Frontiers in Molecular Biosciences, 2020 PurposeBone remodeling is affected by mechanical stimulation. Osteocytes are the primary mechanical load-sensing cells in the bone, and can regulate osteoblast and osteoclast activity, thus playing a key role in bone remodeling. Further, bone mass during
Jingke Du +11 more
doaj +1 more source