Results 31 to 40 of about 19,097 (127)
, 1995 PhDThe insulin-like growth factors, IGF-I and IGF-II, are ubiquitous polypeptide molecules that have mitogenic and metabolic actions in a wide variety of cell types, and consequently play a major role in mammalian growth and development.
Yateman, M.E, Yateman, Martin Edward
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Electrical activity suppresses intrinsic growth competence in adult primary sensory neurons [PDF]
, 2009 The ability of neurons to regenerate in the adult mammalian central nervous system (CNS) is often poor, leading to persistent deficits after injury. Failure of axon regeneration in the CNS has been attributed to the presence of an extrinsic inhibitory ...
Enes, Joana
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The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response
, 2010 The aim of this article is to review current literature on the response of soluble interleukin-6 receptor to exercise and identify a potential role for sIL-6R in skeletal muscle function.
Stevenson, Emma +6 more
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Molecular mechanisms of drug resistance, invasion and metastasis in pancreatic carcinoma [PDF]
, 2008 The research outlined in this thesis aims to further our knowledge of the biological characteristics underlying the aggressive behaviour by which pancreatic cancer invades and metastasises at an early stage and is refractory to most chemotherapeutic ...
Walsh, Naomi
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Characterisation and ontogeny of natural killer cells in Xenopus laevis [PDF]
, 2002 The initial aim of the work described in this Thesis was to investigate the lymphoid organ distribution, phenotype and function of the lymphocyte population identified by candidate anti-Xenopus natural killer (NK) cell monoclonal antibodies (mAb's ...
Stewart, Rebecca
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, 1997 Ciliary neurotrophic factor (CNTF) drives the sequential assembly of a receptor complex containing the ligand-specific a-receptor subunit (CNTFR) and the signal-transducing b-subunits gp130 and leukemia inhibitory factor receptor-b (LIFR).
Ralph Laufer +13 more
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, 2010 Includes abstract.Includes bibliographical references (leaves 121-158).A recent study from the Hapgood laboratory demonstrated the presence of a novel crosstalk mechanism between the glucocorticoid receptor (GR) and gonadotropin-releasing hormone ...
Wehmeyer, Lance
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RNA virus modulation of IFN, PI3K and apoptosis
, 2009 Interferon (IFN) and phosphatidylinositol 3-kinase (PI3K) are apoptosis regulators that are targeted by viruses to promote survival of infected cells.
Killip, Marian J.
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Role of SOCS proteins in FLT3-ITD and BCR/ABL mediated leukemogenesis
, 2010 Acute myeloid/lymphoid leukemia is a fatal hematological malignancy characterized by accumulation of nonfunctional, immature blasts, which interferes with the production of normal blood cells.
Reddy, N. G. Pavan Kumar
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, 2000 peer reviewedLeukemia inhibitory factor (LIF), cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M (OSM) lead to heterodimerization of LIF receptor (LIFR) or the OSM-specific receptor (OSMR) with glycoprotein (gp) 130, the common receptor ...
Heinrich, P. C. +9 more
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