Results 21 to 30 of about 1,692 (168)
mBio, 2016 Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors to injure immune cells and promote infection of its host. Of these proteins, the bicomponent family of pore-forming leukocidins play critical roles in S.
Divya Balasubramanian +11 more
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Binding of pseudomonal leukocidin to rabbit polymorphonuclear leukocytes [PDF]
Infection and Immunity, 1984 The leukocytotoxic toxin pseudomonal leukocidin, produced by Pseudomonas aeruginosa, was radioiodinated with chloramine-T reagent. Binding of [125I]leukocidin to rabbit polymorphonuclear leukocytes was found to be concentration dependent at 37 degrees C.
T, Hirayama +4 more
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Methicillin-susceptible, Doxycycline-resistant Staphylococcus aureus, Côte d’Ivoire
Emerging Infectious Diseases, 2007 We report 2 outbreaks of Panton-Valentine leukocidin–positive, doxycycline-resistant, methicillin-susceptible Staphylococcus aureus infections in French soldiers operating in Côte d’Ivoire.
Olivier Lesens +11 more
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Staphylococcus aureus Extracellular Vesicles: A Story of Toxicity and the Stress of 2020
Toxins, 2021 Staphylococcus aureus generates and releases extracellular vesicles (EVs) that package cytosolic, cell-wall associated, and membrane proteins, as well as glycopolymers and exoproteins, including alpha hemolysin, leukocidins, phenol-soluble modulins ...
Xiaogang Wang +3 more
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Proteomics of Staphylococcus aureus biofilm matrix in a rat model of orthopedic implant-associated infection. [PDF]
PLoS ONE, 2017 The matrix proteins of Staphylococcus aureus biofilm have not been well defined. Previous efforts to identify these proteins were performed using in vitro systems.
Mei G Lei, Ravi Kr Gupta, Chia Y Lee
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Staphylococcal Bicomponent Pore-Forming Toxins: Targets for Prophylaxis and Immunotherapy
Toxins, 2014 Staphylococccus aureus represents one of the most challenging human pathogens as well as a common colonizer of human skin and mucosal surfaces. S. aureus causes a wide range of diseases from skin and soft tissue infection (SSTI) to debilitating and life ...
M. Javad Aman, Rajan P. Adhikari
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Role of Glucose-6-Phosphate in Metabolic Adaptation of Staphylococcus aureus in Diabetes
Microbiology Spectrum, 2021 Diabetic foot ulcer (DFU) is the most common and costly sequela of diabetes mellitus, often leading to lower-extremity amputation with poor 5-year survival rates.
Keun Seok Seo +6 more
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Biomédica: revista del Instituto Nacional de Salud, 2009 En los últimos años se ha informado la aparición de Staphylococcus aureus resistente a la meticilina como causa de infecciones extrahospitalarias graves. En Colombia, en el 2006, se publicó el primer reporte de S. aureus como causa de infección de piel y
Ana María Perilla +7 more
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Staphylococcal leukocidin and .GAMMA.-hemolysin.
Nippon Saikingaku Zasshi, 1997 極めて相同性の高い一次構造を持つ2種類の蛋白質が, 数個のアミノ酸残基の相違により全く異なった機能を持つという事実が Staphylococcus aureus の二成分蛋白毒素ロイコシジンならびにγヘモリジンにおいて明らかにされた。両者は, それぞれヒト白血球および赤血球上で孔を形成する蛋白毒素であるが, ロイコシジンの LukS 成分が, プロテインキナーゼA認識蛋白質であり, 本毒素成分のリン酸化と毒素活性特異性とに強い相関があることが明らかになった。また Panton-Valentine ロイコシジン遺伝子 (lukF-PVおよび lukS-PV) はφPVLと命名された S.
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Virulence, 2018 Pathogenesis of Staphylococcus aureus is increasingly recognized to be driven by powerful toxins. Staphylococcus aureus employs up to six pore-forming toxins to subvert the human host defense and to promote bacterial invasion: alpha-hemolysin that ...
Harald Rouha +11 more
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