Results 11 to 20 of about 33,574 (255)

Total hip and knee replacement surgery results in changes in leukocyte and endothelial markers

Journal of Inflammation, 2010
Background It is estimated that over 8 million people in the United Kingdom suffer from osteoarthritis. These patients may require orthopaedic surgical intervention to help alleviate their clinical condition. Investigations presented here was to test the
Maclean Kirsty M, Edwards David R, Hendricks Beverly D, Hughes Stephen F, Bastawrous Salah S, Middleton Jim F   +5 more
doaj   +1 more source

Hemodialysis membrane-related neutrophil dysfunctions and pentoxifylline - a pilot study [PDF]

, 1990
Hemodialysis treatment is associated with activation of neutrophil granulocytes. Pentoxifylline has been shown to inhibit neutrophil activation in vitro and in vivo.
Hoffmann, H., Jochum, Marianne, Schiffl, H., Spannagl, Michael   +3 more
core   +1 more source

A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage

Pathophysiology, 2021
A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed.
Eric K. Patterson, Nicolas Vanin Moreno, Douglas D. Fraser, Gediminas Cepinskas, Takaya Iida, Roberta A. Berard   +5 more
doaj   +1 more source

Investigation of Midtrimester Amniotic Fluid Factors as Potential Predictors of Term and Preterm Deliveries

Mediators of Inflammation, 2006
Aims. Our aim is to investigate, in 13 cases (delivering preterm) and 21 matched (for age, parity, and gestational age) controls (delivering at term), whether midtrimester amniotic fluid concentrations of elastase, secretory leukocyte proteinase ...
Ariadne Malamitsi-Puchner, Nikolaos Vrachnis, Evi Samoli, Stavroula Baka, George Alexandrakis, Karl-Philipp Puchner, Zoe Iliodromiti, Demetrios Hassiakos   +7 more
doaj   +2 more sources

Indigenous enzymes and leukocyte in sheep milk are markers of health status and physiology of the mammary gland

Italian Journal of Animal Science, 2010
Plasmin, plasminogen and plasminogen activator in ewe bulk milk were not significantly affected by stage of lactation probably as a consequence of the good health of the ewe udders throughout lactation as indicated by SCC which never exceeded 600,000 ...
Agostino Sevi, Laura Schena, Alessandra Marzano, Francesca D’Angelo, Marzia Albenzio   +4 more
doaj   +1 more source

Type I Interferon Receptor Subunit 1 Deletion Attenuates Experimental Abdominal Aortic Aneurysm Formation

Biomolecules, 2022
Objective: Type I interferon receptor signaling contributes to several autoimmune and vascular diseases such as lupus, atherosclerosis and stroke. The purpose of this study was to assess the influence of type I interferon receptor deficiency on the ...
Takahiro Shoji, Jia Guo, Yingbin Ge, Yankui Li, Gang Li, Toru Ikezoe, Wei Wang, Xiaoya Zheng, Sihai Zhao, Naoki Fujimura, Jianhua Huang, Baohui Xu, Ronald L. Dalman   +12 more
doaj   +1 more source

Modulation of HIV Replication in Monocyte-Derived Macrophages (MDM) by Host Antiviral Factors Secretory Leukocyte Protease Inhibitor and Serpin Family C Member 1 Induced by Steroid Hormones

Viruses, 2022
The impact of steroid hormones estrogen and progesterone on human immunodeficiency virus type 1 (HIV-1) replication is well documented. However, the exact mechanism involved in the regulation of HIV-1 replication by estrogen and progesterone is still ...
Santanu Biswas, Emily Chen, Yamei Gao, Sherwin Lee, Indira Hewlett, Krishnakumar Devadas   +5 more
doaj   +1 more source

Single Intramammary Infusion of Recombinant Bovine Interleukin-8 at Dry-Off Induces the Prolonged Secretion of Leukocyte Elastase, Inflammatory Lactoferrin-Derived Peptides, and Interleukin-8 in Dairy Cows

Veterinary Medicine International, 2012
A single intramammary infusion of recombinant bovine interleukin-8 (IL-8) at 50 μg/quarter/head, but not 10 μg/quarter/head, induced clinical mastitis in three of four cows during the dry-off period, resulting in an elevated rectal temperature, redness ...
Atsushi Watanabe, Jiro Hirota, Shinya Shimizu, Shigeki Inumaru, Kazuhiro Kimura   +4 more
doaj   +1 more source

Association between markers of inflammation and indicators of systemic endotoxemia in endogenous psychosis

European Psychiatry, 2022
Introduction The clinical and biological studies indicate the involvement of inflammation in the pathogenesis of endogenous mental disorders. The inflammation markers leukocyte elastase, α1-proteinase inhibitor, and autoantibodies to neuroantigens ...
S. Zozulya, I. Oleichik, I. Otman, M. Yakovlev, T. Klyushnik   +4 more
doaj   +1 more source

The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease

Respiratory Research, 2000
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical properties allow them to efficiently inhibit target enzymes,
Sallenave Jean-Michel
doaj   +1 more source