Results 191 to 200 of about 18,529 (226)

Characterization of leukotriene A4 and B4 bioysnthesis

Prostaglandins, 1983
We have studied LTA4 and LTB4 synthesis in a cell-free system from RBL-1 cells. All the enzymes leading to the formation of LTB4 from arachidonic acid are localized in the soluble fraction (100,000 x g supernatant) of these cells. The formation of LTA4 and LTB4 is complete by 10 min.
B A, Jakschik, C G, Kuo
openaire   +2 more sources

Biosynthesis and biological activity of leukotriene B4

Clinical Biochemistry, 1990
The leukotrienes are a family of biologically active molecules derived from arachidonic acid. While prostaglandins and thromboxanes are products of the cyclooxygenase pathway of arachidonic acid metabolism, the leukotrienes are formed by arachidonate 5-lipoxygenase, an enzyme present in phagocytes, mast cells, and basophils.
P, Borgeat, P H, Naccache
openaire   +2 more sources

Leukotriene-B4 Receptor and Signal Transduction

2000
When cells are stimulated with various agonists, cells release arachidonic acid by the action of phospholipases, and arachidonic acid is further converted to various types of leukotrienes (LTs; Samuelsson et al. 1987; Shimizu and Wolfe 1990; Serhan et al. 1996).
T, Shimizu, T, Yokomizo, T, Izumi
openaire   +2 more sources

PSORIASIS AND LEUKOTRIENE B4

The Lancet, 1982
S D, Brain, R D, Camp, P M, Dowd, A K, Black, P M, Woollard, A I, Mallet, M W, Greaves   +6 more
openaire   +2 more sources

Regulation of the production (leukotriene A4 hydrolase) and the action (leukotriene B4 receptor sites) of leukotriene B4

1987
Leukotriene B4 (LTB4) is a product of arachidonic acid metabolism derived through the action of the 5-lipoxygenase pathway. The end product of the 5-lipoxygenase reaction, LTA4, is converted by a specific enzyme, leukotriene A4 hydrolase, to LTB4 (5[S],12[R]-dihydroxy 6,14-cis-8,10-trans eicosatetraenoic acid).
openaire   +1 more source

Leukotriene B4

General Pharmacology: The Vascular System, 1981
openaire   +2 more sources

Leukotriene A4 hydrolase and leukotriene B4 metabolism

Journal of Lipid Mediators and Cell Signalling, 1995
T, Yokomizo, N, Uozumi, T, Takahashi, K, Kume, T, Izumi, T, Shimizu   +5 more
openaire   +2 more sources

Dipyridamole Inhibits Leukotriene B4 Synthesis

Thrombosis and Haemostasis, 1987
GRESELE, Paolo, J. Arnout, J. Vermylen
openaire   +3 more sources

A Second Leukotriene B4 Receptor, Blt2

Journal of Experimental Medicine, 2000
Takehiko Yokomizo, Kazuhiko Kato, Takashi Izumi   +2 more
exaly  

Specific binding of leukotriene B4 to a receptor on human polymorphonuclear leukocytes.

Journal of Experimental Medicine, 1983
C W Parker, Parker C W
exaly