Results 131 to 140 of about 25,256 (244)

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics

open access: yesEpilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis evaluating the efficacy and safety of fenfluramine in patients with Dravet syndrome stratified by age, number of previously attempted antiseizure medications, and SCN1A pathogenic variant status using data pooled from the three pivotal randomized controlled trials ...
Rima Nabbout   +20 more
wiley   +1 more source

DECREASE study: A European pool‐analysis of patients with significant reductions in concomitant antiseizure medications in cenobamate Early Access Programs

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs). Method Anonymized patient data from real‐world studies/registries associated with European cenobamate EAPs were pooled.
Vicente Villanueva   +25 more
wiley   +1 more source

Rare genetic variation in adults with surgically treated temporal lobe epilepsy: An exome sequencing study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To determine the frequency of monogenic variants and pathogenic copy number variants (CNVs) in adults with surgically treated temporal lobe epilepsy (TLE). Methods We performed exome sequencing (ES), including CNV analysis, in 45 adults with TLE who had previously undergone epilepsy surgery.
Antonia P. Pirker   +12 more
wiley   +1 more source

Utilization of Anti-Seizure Medication (ASMS) and Seizure Control in Pediatric Epilepsy: A Retrospective Cross-Sectional Study in Oman. [PDF]

open access: yesHealthcare (Basel)
Nomier Y   +6 more
europepmc   +1 more source

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

open access: yesEpilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley   +5 more
wiley   +1 more source

Outcomes of patients with post‐stroke epilepsy: A scoping review on quality of life, readmissions, costs, seizure recurrence, and medication adherence

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Post‐stroke epilepsy (PSE) affects ≈10% of patients with stroke and is associated with adverse health and economic outcomes. We aimed to review published literature on health and economic outcomes for patients with PSE, with a specific focus on quality of life, hospital readmissions, healthcare costs, seizure recurrence, and ...
Nega Dagnew Baye   +5 more
wiley   +1 more source

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