Transcranial Magnetic Stimulation as a Translational Biomarker in Early-Phase Anti-Seizure Medication Development: A Randomized, Double-Blind, Placebo-Controlled Study in Generalized Epilepsy. [PDF]
de Cuba CME +7 more
europepmc +1 more source
Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort
Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam +8 more
wiley +1 more source
Levetiracetam inhibits the Na<sup>+</sup> HCO<sub>3</sub> <sup>-</sup> transporter Ncbe/NBCn2 (Slc4a10) in the choroid plexus of mice. [PDF]
Johnsen LØ +4 more
europepmc +1 more source
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard +33 more
wiley +1 more source
Gabapentin and cognitive impairment after traumatic brain injury: A multinational cohort of 49,925 patients. [PDF]
Thorman IB +20 more
europepmc +1 more source
Levetiracetam and Peripheral Oxidative Stress Biomarkers in Epilepsy: A Systematic Review of Human Evidence. [PDF]
Mîndreanu R +6 more
europepmc +1 more source
Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy +3 more
wiley +1 more source
Short-Term Renal Effects of Add-On Levetiracetam in Client-Owned Dogs with Idiopathic Epilepsy Receiving Phenobarbital: A Four-Week Prospective Study. [PDF]
Kankitpaisan U +3 more
europepmc +1 more source
Shared struggles: Parallels in caregiver burden between canine and paediatric epilepsy
Abstract Background Disease‐specific aspects of pet owners’ caregiver burden could be missed by generic burden measures. This study aimed to assess whether a framework developed to describe caregiver burden in parents of children with epilepsy was applicable to caregivers of dogs with epilepsy.
Zoe Belshaw, Rowena M. A. Packer
wiley +1 more source

