Epilepsia Open, EarlyView.Abstract Objective To evaluate the real‐world effectiveness, safety, and treatment retention of cenobamate (CNB) in patients with drug‐resistant epilepsy (DRE), including ultra‐refractory epilepsy (URE), high seizure burden, and extensive prior treatment history.
Ondřej Strýček +9 more
wiley +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Differences in Survival Associated With the First Antiseizure Medication in People With Dementia and Epilepsy. [PDF]
NeurologyZelano J +3 more
europepmc +1 more source
Psychotic disorder related to levetiracetam usage: report of two cases
, 2009 Levetiracetam is an antiepileptic agent and its mechanism of action is not exactly known. It has been suggested that It could be used in the treatment of movement disorders, tardive dyskinesia, and some psychiatric disorders, beside epilepsy ...
Erdogan, Serap +2 more
core
Journal of Hospital Medicine, EarlyView.Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx +9 more
wiley +1 more source
Efficacy and safety of levetiracetam intravenous infusion combined with midazolam continuous pump infusion for stepwise emergency treatment of convulsive status epilepticus in children: a retrospective cohort study. [PDF]
Am J Transl ResZhang Y, Liu Y, Pan N, Yang Y.
europepmc +1 more source
Trends in antiseizure medication monotherapy for pediatric epilepsy in the United States. [PDF]
Epilepsia OpenOstendorf AP +6 more
europepmc +1 more source
Levetiracetam and Rhabdomyolysis: A Rare but Clinically Significant Adverse Effect. [PDF]
CureusAbabio PA +5 more
europepmc +1 more source
Placebo Effect in Levodopa‐Induced Dyskinesia: A Systematic Review and Meta‐Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background Levodopa‐induced dyskinesia (LID) is a complication of Parkinson's disease (PD) treatment. While the placebo effect is a known component in PD clinical trials, its specific magnitude in the context of LID is not well characterized.
Luiz Vinicius Silva Correa +5 more
wiley +1 more source
Orthostatic Myoclonus—Clinical and Electrophysiological Features in a Large Retrospective Cohort
Movement Disorders Clinical Practice, EarlyView.Abstract Background Orthostatic myoclonus is characterized by irregular, lower limb myoclonic bursts during stance and is a major cause of postural instability and falls. However, studies are limited, and little is known about its pathophysiology. Objectives We sought to define the clinical and electrophysiological features of orthostatic myoclonus in ...
Sai A. Nagaratnam +8 more
wiley +1 more source