Results 141 to 150 of about 28,601 (275)

Impact of cenobamate on cortical responses to transcranial magnetic stimulation in people with drug‐resistant focal epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Cenobamate (CNB) is an effective antiseizure medication, though its mechanisms of efficacy remain incompletely understood. We assessed changes in cortical responses to transcranial magnetic stimulation (TMS) following CNB treatment.
Silvano R. Gefferie, Diego Jiménez‐Jiménez, Gerhard H. Visser, Robert M. Helling, Arn M. J. M. van den Maagdenberg, Josemir W. Sander, Simona Balestrini, Roland D. Thijs   +7 more
wiley   +1 more source

Comparing the safety and efficacy of sodium valproate, levetiracetam, and phenytoin in attenuating the severity of agitation in patients with post-traumatic brain injury: An observational study. [PDF]

PLoS One
Singh S, Nayak R, Gangachannaiah S, Bhosale A, Parveen RS, Kumar S G V, Sundar G.   +6 more
europepmc   +1 more source

Progressive myoclonus epilepsy in Down syndrome with Alzheimer's disease: An 11‐year longitudinal study and proposed diagnostic red flags

Epilepsia Open, EarlyView.
Abstract Objective Individuals with Down syndrome (DS) face an ultra‐high risk of Alzheimer's disease (AD). Within this continuum, Progressive Myoclonus Epilepsy (PME) has emerged as a marker of advanced neurodegeneration. Building on our 2014 characterization of this syndrome, we aimed to define its long‐term natural history and pathological substrate.
Giuseppe d'Orsi, Ezio Calò, Maria Teresa Di Claudio, Carmela Pia Ferro, Umberto Costantino, Elio Perrone, Raffaela Rita Latino   +6 more
wiley   +1 more source

Effectiveness and safety of implantable vagus nerve stimulation in people with primary generalized tonic–clonic seizures

Epilepsia Open, EarlyView.
The impact of prompt diagnosis and treatment, and early predictors of outcome severity in this cohort. Abstract Objective Most therapies for drug‐resistant epilepsy (DRE) focus on focal‐onset seizures, the most common seizure types. Studying primary generalized tonic–clonic seizures (PGTCS) is more challenging due to diagnostic and recruitment ...
Katherine Eggleston, Justine Curley, Ryan Verner, Maxine Dibue, Charles Gordon, Gaia Giannicola, Kathryn Nichol   +6 more
wiley   +1 more source

Preoperative Seizure Control and Perioperative Anesthetic Outcomes in Children Receiving Levetiracetam Versus Phenytoin: A Hospital-Based, Prospective, Comparative Cohort Study. [PDF]

Cureus
Agarwal A, Shah PV, Shah PS, Pathak S, Meena R.   +4 more
europepmc   +1 more source

Hypersensitivity reaction risk when restarting cenobamate after discontinuation: Insights from a prolonged hospitalized cohort

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the risk of hypersensitivity reactions, including dermatological rashes, when cenobamate (CNB) is restarted at maintenance doses after temporary discontinuation. Methods We leveraged the natural experiment of long antiseizure medication discontinuation during intracranial EEG evaluation and conducted a retrospective ...
Marina Feldman, Andreas Alexopoulos, Juan Bulacio, Dileep Nair, Vineet Punia   +4 more
wiley   +1 more source

<i>Caenorhabditis</i> Intervention Testing Program: the anticonvulsant levetiracetam does not extend lifespan in nematodes. [PDF]

MicroPubl Biol
Akella JS, Onken BD, Sedore CA, Song Y, Achanta VM, Walker M, Xue J, Guo S, Coleman-Hulbert A, Phillips PC, Lithgow GJ, Driscoll M.   +11 more
europepmc   +1 more source

Levetiracetam induced drug reaction with eosinophilia and systemic symptoms (DRESS)

, 2019
Drug reaction with eosinophilia and systemic symptom (DRESS) is a severe adverse drug reaction characterized by rash, fever, lymphadenopathy and internal organ involvement.
Ismail, Rasimah, Goh, Siew Wen, Arumugam, Mohan, Jamil, Adawiyah, Elengoe, Asita, Periyasamy, Petrick   +5 more
core  

Occurrence and clinical correlates of depressive symptoms in adults with epilepsy: A study in Georgia

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the occurrence, clinical correlates, and screening accuracy of depressive symptoms (DS) among adults with epilepsy in Georgia, a country with limited mental health resources. Methods We conducted a cross‐sectional study in adults with epilepsy attending a tertiary care center. We assessed DS using two validated tools: the
Ketevan Silagadze, Eka Burkadze, Maka Areshidze, Teimuraz Silagadze, Sofia Kasradze, Josemir W. Sander   +5 more
wiley   +1 more source

Evaluation of Neuropsychiatric Events in Patients Receiving Levetiracetam for Seizure Prophylaxis Following Traumatic Brain Injury. [PDF]

J Pharm Technol
Ammoscato MJ, Evers AN, Partington JR, Reinert JP.   +3 more
europepmc   +1 more source