Results 71 to 80 of about 25,256 (244)

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

open access: yesEpileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa   +7 more
wiley   +1 more source

Efficacy of Levetiracetam Use in Neonatal Seizure: A Retrospective Cohort Study

open access: yesNeuroSci
Neonatal seizures are common complications in neonatal intensive care units. They have been noticed to be more common in preterm infants, but they can also affect term infants. Levetiracetam is a broad-spectrum antiepileptic drug that has been studied to
Faisal Aqeel Alsehli   +12 more
doaj   +1 more source

Levetiracetam Affects Differentially Presynaptic Proteins in Rat Cerebral Cortex

open access: yesFrontiers in Cellular Neuroscience, 2017
Presynaptic proteins are potential therapeutic targets for epilepsy and other neurological diseases. We tested the hypothesis that chronic treatment with the SV2A ligand levetiracetam affects the expression of other presynaptic proteins.
Daniele Marcotulli   +7 more
doaj   +1 more source

Aphasic status epilepticus due to Epstein–Barr virus meningoencephalitis – A clinical vignette

open access: yes
Epileptic Disorders, EarlyView.
Gemma Bassani   +6 more
wiley   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini   +6 more
wiley   +1 more source

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen   +4 more
wiley   +1 more source

Epilepsy with eyelid myoclonia beyond the classical phenotype: Longitudinal electroclinical observations in a pediatric cohort

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Epilepsy with eyelid myoclonia is a childhood‐onset generalized epilepsy syndrome with variable recognition of eyelid myoclonia, eye‐closure sensitivity, and photosensitivity during follow‐up. We aimed to characterize longitudinal clinical and electroencephalographic features in pediatric epilepsy with eyelid myoclonia, focusing on ...
Hande Aygün   +3 more
wiley   +1 more source

A meta-analysis of randomized controlled trials on levetiracetam in the treatment of pediatric patients with epilepsy

open access: yesNeuropsychiatric Disease and Treatment, 2018
Lanlan Zhang,1 Chengzhong Wang,1 Wei Li2 1Department of Pediatric Neurology, Yancheng Maternal and Child Health Hospital, 2Department of Medical Imaging, Jiangsu Vocational College of Medicine, Yancheng, China Objective: To evaluate clinical efficacy ...
Zhang LL, Wang CZ, Li W
doaj  

Sustained seizure freedom with fenfluramine for refractory epilepsy due to 7q32‐q34 deletion syndrome

open access: yes
Epileptic Disorders, EarlyView.
Divya Veerapaneni   +2 more
wiley   +1 more source

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