Parkinson's disease is the second-most common neurodegenerative disorder worldwide. Besides deciphering the mechanisms that underlie the etiology of the disease, it is important to elucidate the factors that influence the efficacy of the treatment ...
Sebastiaan P. van Kessel, Sahar El Aidy
doaj +1 more source
Buried bumper syndrome in percutaneous endoscopic gastrostomy with a jejunal extension tube in patients undergoing levodopa–carbidopa intestinal gel treatment [PDF]
Masatoshi Nakagawa +9 more
openalex +1 more source
‘Levodopa Phobia’: a review of a not uncommon and consequential phenomenon
‘Levodopa Phobia’ is under-recognised in Parkinson’s disease but can cause profound detrimental clinical complications if left to continue. Several types can be encountered in clinical practice and can be driven by a misplaced fear of levodopa-induced ...
N. Titova +3 more
semanticscholar +1 more source
Adaptive Deep Brain Stimulation Benefits: Younger Patients with Persistent Wearing‐off Symptoms
Abstract Background Parkinson's disease (PD) often involves motor fluctuations and dyskinesia, which are difficult to manage with medication alone. Conventional deep brain stimulation (cDBS) effectively alleviates symptoms but has limitations, including the challenge of balancing therapeutic effects against potential side effects, as well as limited ...
Takuto Emura +11 more
wiley +1 more source
The impact of sleep quality on cognitive functioning in Parkinson's disease [PDF]
In healthy individuals and those with insomnia, poor sleep quality is associated with decrements in performance on tests of cognition, especially executive function. Sleep disturbances and cognitive deficits are both prevalent in Parkinson's disease (PD).
Bogdanova, Y. +4 more
core +4 more sources
Ethnic and Gender Disparities in Access to Deep Brain Stimulation Surgery for Parkinson's Disease
Abstract Background Deep brain stimulation (DBS) is an established treatment for Parkinson's disease (PD) in appropriately selected patients. DBS may be underused in certain patient populations, especially women and racialized groups. Barriers and biases to receiving DBS that could account for underuse among these groups are not well studied in Canada.
Fang Ba +14 more
wiley +1 more source
Paolo Solla, Antonino Cannas, Francesco Marrosu, Maria Giovanna MarrosuMovement Disorders Center, Institute of Neurology, University of Cagliari, Cagliari, ItalyAbstract: Parkinson disease (PD) is a neurodegenerative disorder characterized by 3 cardinal ...
Paolo Solla +3 more
doaj
Sleep disturbance and serum ferritin levels associate with high impulsivity and impulse control disorders in male Parkinson\u27s Disease patients [PDF]
Impulse control disorders (ICDs) occur in a subset of Parkinson’s disease (PD) patients on dopaminergic medications however there are currently no reliable markers to identify patients at risk.
Anderton, R +6 more
core +1 more source
The Acute Brain Response to Levodopa Heralds Dyskinesias in Parkinson Disease [PDF]
OBJECTIVE: In Parkinson disease (PD), long‐term treatment with the dopamine precursor levodopa gradually induces involuntary “dyskinesia” movements. The neural mechanisms underlying the emergence of levodopa‐induced dyskinesias in vivo are still poorly ...
Christensen, Mark S. +6 more
core +1 more source
Levodopa treatment and dendritic spine pathology
Parkinson's disease (PD) is a neurodegenerative disorder associated with the progressive loss of nigrostriatal dopaminergic neurons. Levodopa is the most effective treatment for the motor symptoms of PD.
H. Nishijima +4 more
semanticscholar +1 more source

