Results 111 to 120 of about 91,122 (346)

Serious Illness Conversation in the Care of Atypical Parkinsonian Disorders: A Practical Guide for Neurology Clinicians

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Compared to Parkinson's disease, atypical parkinsonian disorders (APD) are characterized by a more rapidly progressive course, often leading to profound disability. Effective communication between clinicians, patients, and care partners is essential to support patient‐centered care and shared decision‐making.
Michiko K. Bruno, Jocelyn Jiao, Neha M. Kramer, Margaret Ivancic, Claudia Chou, Jessica Shurer, Thomas Carroll, on behalf of CurePSP Centers of Care Palliative Care Working Group   +7 more
wiley   +1 more source

Neuropathology of Lewy body dementia: Lewy-related pathology, α-synuclein oligomers, and comorbid pathologies

Molecular Neurodegeneration
Lewy body dementia is the second most common form of neurodegenerative dementia, following Alzheimer’s disease. This umbrella term encompasses dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD).
Hiroaki Sekiya, Tomoyasu Matsubara, Michael A. DeTure, Dennis W. Dickson   +3 more
doaj   +1 more source

An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

Molecular Brain, 2017
Lewy body dementias are the second most common cause of neurodegenerative dementia in the elderly after Alzheimer’s disease (AD). The two clinical subgroups of Lewy body dementias, namely, dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (
Arnab Datta, Yuek Ling Chai, Jing Min Tan, Jasinda H. Lee, Paul T. Francis, Christopher P. Chen, Siu Kwan Sze, Mitchell K. P. Lai   +7 more
doaj   +1 more source

Management of rapid eye movement sleep behavior disorder in patients with Parkinson's disease [PDF]

, 2016
Among all of the devastating effects that Parkinson’s disease (PD) has on an individual, sleep dysfunction is one that can have a profound effect on the entire family of the patient. The most potentially destructive of these sleep syndromes being that of
Jeffries, Michael
core   +1 more source

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in alzheimer’s disease and parkinson’s disease [PDF]

, 2017
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases of the elderly people that have devastating effects in terms of morbidity and mortality.
Chakrabarti, S., Chatterjee, U., Ganguly, G., Saso, L.   +3 more
core   +3 more sources

Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam, Remarh Bsoul, Gunhild Waldemar, Steen Gregers Hasselbalch, Anja Hvid Simonsen, Marie Bruun, Laura Storm Næsborg Andersen, Christian von Buchwald, Kasper Aanæs, Christian K. Pedersen, Ida S.B. Andersen, Magne Bech, Clara Hageman Pinborg, Aušrinė Areškevičiūtė, Eva Løbner Lund, Kristian Steen Frederiksen   +15 more
wiley   +1 more source

Baseline and Six‐Month Actigraphy and Sleep‐monitoring Devices Help Differentiate Between Alzheimer’s Disease and Dementia with Lewy Bodies [PDF]

, 2023
Debby W. Tsuang, Karl Brown, Andrew Shutes‐David, Sarah Payne, Adrienne Jankowski, Edmund Seto, Erik K. St. Louis, Daniel J. Levendowski, Katie Wilson   +8 more
openalex   +1 more source

Low Frequency of Dementia with Lewy Bodies Diagnosis in a Colombian Memory Clinic

Movement Disorders Clinical Practice, EarlyView.
Abstract Background The global burden of dementia is increasing, particularly in low‐ and middle‐income countries. Dementia with Lewy bodies (DLB) is the second most common neurodegenerative dementia but remains underreported and frequently misdiagnosed. Its prevalence in Latin America is largely unknown.
Felipe Botero‐Rodríguez, José Manuel Santacruz‐Escudero, Miguel Germán Borda, Salomón Salazar‐Londoño, Carlos Cano‐Gutiérrez, Dag Aarsland, on behalf of COL‐DLB   +6 more
wiley   +1 more source

Using plasma ptau181 in Lewy Body Disease spectrum for the identification of Alzheimer’s disease co‐pathology [PDF]

, 2023
Carla Abdelnour, Marian Shahid, Alena Smith, Edward N. Wilson, Hillary Vossler, Melani J. Plastini, Christina B. Young, Joseph R. Winer, Geoffrey A. Kerchner, Katrin I. Andreasson, Victor W. Henderson, Elizabeth C. Mormino, Kathleen L. Poston   +12 more
openalex   +1 more source

Prognostic Value of Parkinson's Disease Subtypes in the LABS‐PD Cohort: Functional Ability, Quality of Life and Mortality

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash, Shirley Eberly, David Oakes, David Grimes, Anthony E. Lang, Caroline Tanner, Tiago A. Mestre, Connie Marras   +7 more
wiley   +1 more source