Results 231 to 240 of about 91,122 (346)
Glacier‐Atmosphere Interactions and Feedbacks in High‐Mountain Regions ‐ A Review
Abstract Mountain glaciers are among the natural systems most vulnerable to climate change. However, their interactions with the atmosphere are complex and not fully understood. These interactions can trigger rapid adjustments and climate feedbacks that either amplify or attenuate atmospheric signals, influencing both glacier response and large‐scale ...
T. Sauter +17 more
wiley +1 more source
Sialylation patterns in cerebral amyloid angiopathy
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau +8 more
wiley +1 more source
x‐ray phase‐contrast tomography enabled three‐dimensional, label‐free visualization and quantification of protein aggregates in neurodegenerative diseases with isotropic submicrometer resolution. The study revealed distinct electron density patterns in Lewy bodies, Hirano bodies, granulovacuolar degeneration, and amyloid plaques, highlighting their ...
Jonas Franz +9 more
wiley +1 more source
Comments on “Impact of Neuropsychiatric Symptoms on Caregiver Burden in Major Neurocognitive Disorder due to Lewy Body Disease: A Bibliometric Analysis” [PDF]
Mohammad Idrees +4 more
openalex +1 more source
ABSTRACT Modelling the evolution of Alzheimer's disease (AD) requires a thorough spatiotemporal study of longitudinal neuroimaging data. We propose in this paper a novel deep learning framework that uses a parallel combination of Recurrent Neural Networks (RNNs) and Vision Transformers (ViT) to extract temporal disease dynamics and spatial structural ...
Sahbi Bahroun, Gwanggil Jeon
wiley +1 more source
Targeting BPOZ-2 in Lewy body disease
Avik Roy
doaj +1 more source
Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava +9 more
wiley +1 more source
Is there a preference for PET or SPECT brain imaging in diagnosing dementia? The views of people with dementia, carers, and healthy controls [PDF]
Cam Donaldson +10 more
core +1 more source
Formation of Condition‐Dependent Alpha‐Synuclein Fibril Strain in Artificial Cerebrospinal Fluid
α‐synuclein aggregation in artificial cerebrospinal fluid (aCSF) leads to a distinct conformation with an electron density pocket motif found in aggregates from PD and MSA patients. Such fibrils has low stability outside the reaction conditions, hinting about the influence of cerebrospinal fluid components not only on the formation, but also on the ...
Rūta Sniečkutė +7 more
wiley +1 more source

