Results 241 to 250 of about 91,122 (346)

Parkinson\u27s disease and multiple system atrophy have distinct α-synuclein seed characteristics [PDF]

, 2019
Cairns, Nigel J., Dhavale, Dhruva D., Diamond, Marc I., Furman, Jennifer L., Holmes, Brandon B., Kotzbauer, Paul T., Song, Eun-Suk, Su, Bryant W., Yamasaki, Tritia R.   +8 more
core   +1 more source

Reduced triacylglycerols and lipid droplets are associated with resilience to Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Although it has become clear that alterations in lipid metabolism are associated with Alzheimer's disease (AD), it is unclear how they contribute to both cognitive decline and the pathophysiology of AD. METHODS Lipidomics and activity‐based protein profiling (ABPP) were performed in the frontal cortex of control, AD and resilient ...
Daan van der Vliet, Luuk E. de Vries, Xinyu Di, Dennis Wever, Brechtje de Jong, Marc T. C. van der Meij, Marielle van der Peet, Amy C. Harms, Thomas Hankemeier, Dick F. Swaab, Inge Huitinga, Joost Verhaagen, Mario van der Stelt   +12 more
wiley   +1 more source

Putaminal hypermetabolism identifies Lewy body co-pathology in Alzheimer's disease. [PDF]

Alzheimers Dement
Kang S, Jeon S, Kim Y, Jeon SH, Choi M, Lee YG, Ye BS, Alzheimer's Disease Neuroimaging Initiative.   +7 more
europepmc   +1 more source

APOE4 and cognition in intracranial atherosclerosis: beyond Alzheimer's pathology

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The apolipoprotein E ε4 (APOE ε4) allele is a major genetic risk factor for Alzheimer's disease, but its relevance to cognition in intracranial atherosclerosis (ICAS) remains unclear. We investigated the association between APOE ε4 and cognition in ICAS. METHODS Baseline data from a multicenter cohort were analyzed.
Anqi Cheng, Yinxi Zou, Linwen Liu, Hebo Wang, Zhibing Ai, Shiwen Wu, Qianqian Si, Yiyang Liu, Huanyu Zhou, Haoyao Guo, Qiuyu Yu, Zijue Wang, Mingli Li, Caiyan Liu, Weihai Xu   +14 more
wiley   +1 more source

Regional cortical network atrophy predicts progression to dementia in the Lewy body diseases. [PDF]

Alzheimers Dement
Ye R, Pereira TP, Locascio JJ, Goodheart AE, Peterec EC, Brickhouse M, Dickerson BC, Touroutoglou A, Gomperts SN.   +8 more
europepmc   +1 more source

Association between brain volume and depression in Alzheimer's disease: Neuroimaging insights

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) often co‐occurs with depression, affecting cognitive function and quality of life. Understanding the neurobiological links between brain abnormalities and depressive symptoms is essential for effective treatment.
Chao Tang, Jiaxin Yang, Xiaoyang Lei, Ming Zhang, Yi Chen, Xiaoxue Peng, Dian He   +6 more
wiley   +1 more source

Urinary tract infection‐related delirium in Alzheimer's disease and related dementias: Clinical challenges and translational opportunities

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease and related dementias (ADRD) affects millions of patients worldwide and is a leading cause of morbidity in older adults. Patients with ADRD are particularly susceptible to developing urinary tract infection (UTI) and UTI‐related delirium, creating a self‐perpetuating cycle in which ADRD increases vulnerability to infection ...
Sarah Kim, Sarah Kremen, Itai Danovitch, Shouri Lahiri   +3 more
wiley   +1 more source