Results 61 to 70 of about 1,469,506 (316)

datos.bne.es: A library linked dataset [PDF]

open access: yes, 2012
We describe the datos.bne.es library dataset. The dataset makes available the authority and bibliography catalogue from the Biblioteca Nacional de España (BNE, National Library of Spain) as Linked Data.
Gómez-Pérez, A.   +2 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Interoperabilità giuridica: rendere i dati (pubblici) aperti compatibili con imprese e comunità online

open access: yesJLIS.it, 2013
"Legal interoperability" could be defined as the possibility of legally mixing data coming from different sources (including governmental data, data generated by online communities and data held by private parties).
Federico Morando
doaj   +1 more source

CloudTree: A Library to Extend Cloud Services for Trees

open access: yes, 2015
In this work, we propose a library that enables on a cloud the creation and management of tree data structures from a cloud client. As a proof of concept, we implement a new cloud service CloudTree.
Ji, Yanqing   +3 more
core   +1 more source

UT Linked Data Informal Learning Discussion Series Bibliography [PDF]

open access: yes, 2019
The following bibliographies were created as part of the UT Linked Data Informal Learning Discussion Series hosted at UT LibrariesThe following bibliographies were created as part of the UT Linked Data Informal Learning Discussion Series hosted at UT ...
Carbajal, Itza
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Burosumab therapy in children with x-linked hypophosphatemia [PDF]

open access: yes, 2018
BACKGROUND X-linked hypophosphatemia is characterized by increased secretion of fibroblast growth factor 23 (FGF-23), which leads to hypophosphatemia and consequently rickets, osteomalacia, and skeletal deformities.
Boot, Annemieke M   +13 more
core   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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