Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs [PDF]
, 2008 The insulin/IGF-like signalling (IIS) pathway has diverse functions in all multicellular organisms, including determination of lifespan. The seven insulin-like peptides (DILPs) in Drosophila are expressed in a stage- and tissue-specific manner.
Vinti, Giovanna +9 more
core +6 more sources
Identification of sur2 mutation affecting the lifespan of fission yeast [PDF]
, 2021 Yeast is a suitable model system to analyze the mechanism of lifespan. In this study, to identify novel factors involved in chronological lifespan, we isolated a mutant with a long chronological lifespan and found a missense mutation in the sur2^+ gene ...
Ihara, Kunio +7 more
core +1 more source
The gustatory system influences "Drosophila" lifespan [PDF]
, 2011 The lifespan of an organism is affected by the complex interplay between genetic and environmental factors. In C. elegans, this interaction between genes and environment is mediated by the sensory system.
Ostojić, Ivan
core +1 more source
Extension of Yeast Chronological Lifespan by Methylamine [PDF]
, 2012 Background: Chronological aging of yeast cells is commonly used as a model for aging of human post-mitotic cells. The yeast Saccharomyces cerevisiae grown on glucose in the presence of ammonium sulphate is mainly used in yeast aging research.
Lefevre Sophie D. +16 more
core +3 more sources
Molecular evolution and functional characterization of Drosophila insulin-like peptides [PDF]
, 2010 Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway plays key roles in growth, metabolism, stress resistance, reproduction, and ...
Andrews, T Daniel +4 more
core +5 more sources
Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan [PDF]
, 2015 Several pathways modulating longevity and stress resistance converge on translation by targeting ribosomal proteins or initiation factors, but whether this involves modifications of ribosomal RNA is unclear.
Wilson, Iain B H +31 more
core +2 more sources
Day2day: investigating daily variability of magnetic resonance imaging measures over half a year
BMC Neuroscience, 2017 Background Most studies of brain structure and function, and their relationships to cognitive ability, have relied on inter-individual variability in magnetic resonance (MR) images.
Elisa Filevich +8 more
doaj +1 more source
Identification of a novel protein kinase that affects the chronological lifespan in fission yeast [PDF]
, 2017 Chronological lifespan is defined by how long a cell can survive in a non-dividing state. In yeast, it is measured by viability after entry into the stationary phase.
Ihara, Kunio +7 more
core +1 more source
Obstructive Sleep Apnea and Circulating Potassium Channel Levels
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundCardiac arrhythmias and sudden cardiac death are more frequent in patients with obstructive sleep apnea (OSA). OSA is associated with QT prolongation, and QT prolongation is an independent risk factor for sudden cardiac death.
Ning Jiang +9 more
doaj +1 more source
Incentive motivation improves numerosity discrimination in children and adolescents
Scientific Reports, 2022 We recently showed that incentive motivation improves the precision of the Approximate Number System (ANS) in young adults. To shed light on the development of incentive motivation, the present study investigated whether this effect and its underlying ...
Luca Spliethoff, Shu-Chen Li, Annika Dix
doaj +1 more source