Results 171 to 180 of about 2,433,325 (381)

Perturbing the Copper(III)–Hydroxide Unit through Ligand Structural Variation

, 2015
Debanjan Dhar, Gereon M. Yee, Andrew D. Spaeth, David W. Boyce, Hongtu Zhang, Büşra Dereli, Christopher J. Cramer, William B. Tolman   +7 more
openalex   +1 more source

Near-Edge Ligand Stripping and Robust Radiative Exciton Recombination in CdSe/CdS Core/Crown Nanoplatelets [PDF]

, 2020
Jari Leemans, Shalini Singh, Chen Li, Stephanie ten Brinck, Sara Bals, Ivan Infante, Iwan Moreels, Zeger Hens   +7 more
openalex   +1 more source

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

Advanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau, Monica A. Rionda, Evelyn Cho, Jamison G. Clark, Robin E. Kruger, Ruth K. Chan‐Sui, Vasantha Padmanabhan, Molly B. Moravek, Ariella Shikanov   +8 more
wiley   +1 more source

Computed ligand effects on the oxidative addition of phenyl halides to phosphine supported palladium(0) catalysts

, 2014
Claire L. McMullin, Natalie Fey, Jeremy N. Harvey   +2 more
openalex   +2 more sources

Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro

Advanced Biology, EarlyView.
Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi, Paola Fulghieri, Abdurakhmon Aduvaliev, Karen Soffiantini, Irene Oldrati, Margherita Cavallo, Marco Biggiogera, Giorgia Pellavio, Umberto Laforenza, Monica Savio, Virginie Sottile   +10 more
wiley   +1 more source

Toll‐like receptor expression during inflammatory processes in human diseases

Rheumatology & Autoimmunity
Multi‐cellular organisms, including humans, have evolved immune systems as defense mechanisms against pathogens. The immune system employs the Toll‐like receptor (TLR) family as its primary defensive mechanism against infections.
Prashant K. Dhakad, Raghav Mishra, Isha Mishra   +2 more
doaj   +1 more source

Osteocytes under Mechanical Loading Regulate PC‐3 Cancer Cell–Mineral Interactions during Early‐Stage Metastasis to Bone

Advanced Biology, EarlyView.
In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman, Bryan Guo, William W. Du, Burton Yang, Yu Sun, Lidan You   +5 more
wiley   +1 more source

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease

, 2016
J Jerábek, Elisa Uliassi, Laura Guidotti, Jan Korábečný, Ondřej Soukup, Vendula Šepsová, Martina Hrabinová, Kamil Kuča, Manuela Bartolini, Emiliano Peña‐Altamira, Sabrina Petralla, Barbara Monti, Marinella Roberti, María Laura Bolognesi   +13 more
openalex   +1 more source

The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release [PDF]

, 2021
Stefan Düsterhöft, Selcan Kahveci-Türköz, Justyna Wozniak, Anke Seifert, Petr Kašpárek, Henrike Ohm, Shixin Liu, Jana Kopkanova, Juliane Lokau, Christoph Garbers, Christian Preisinger, Radislav Sedláček, Matthew Freeman, Andreas Ludwig   +13 more
openalex   +1 more source

Engineering the Link: From Genome Interaction Maps to Functional Insight

Advanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann, Dominik Niopek   +5 more
wiley   +1 more source